Evidence map›Paper›PMID 28678440›Full record

ArticleCurrent protocols in molecular biology2017

Automated Computational Processing of 3-D MR Images of Mouse Brain for Phenotyping of Living Animals.

Christopher S Medina, Brett Manifold-Wheeler, Aaron Gonzales, Elaine L Bearer

Abstract read
In one paragraph

Article in Current protocols in molecular biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.7field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Quality Assurance Strategies for Brain State Characterization by MEMRI.bioRxiv : the preprint server for biology · 2026
    Article
  2. Reconfiguration of brain-wide neural activity after early life adversity.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  3. Reconfiguration of brain-wide neural activity after early life adversity.bioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Review
  6. Article
  7. Imaging the evolution acute fear: Longitudinal whole brain imaging in living mice of neural activity with MEMRI.Proceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition. International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition · 2019
    Article
  8. Article
  9. Article
  10. Neural activation imaged by MEMRI in mouse models of PTSD: Early Life Stress and Role of the Serotonergic System in Prolonged Response to Fear.Proceedings of the International Society for Magnetic Resonance in Medicine ... Scientific Meeting and Exhibition. International Society for Magnetic Resonance in Medicine. Scientific Meeting and Exhibition · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Christopher S MedinaUniversity of New Mexico Health Sciences Center, Albuquerque, New Mexico.
Brett Manifold-WheelerUniversity of New Mexico Health Sciences Center, Albuquerque, New Mexico.
Aaron GonzalesUniversity of New Mexico Health Sciences Center, Albuquerque, New Mexico.
Elaine L BearerUniversity of New Mexico Health Sciences Center, Albuquerque, New Mexico.
University of New Mexico · US

Funding

UNM TRAININGP50GM085273 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI EDWARDS, JEREMY S · 2009 to 2018
$26.1M
Live imaging of brain circuitry in mouse models of PTSDR01MH096093 · NIMH · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI BEARER, ELAINE L · 2012 to 2016
$2.8M
In Vivo Detection of Neuronal ActivityR01DA018184 · NIDA · CALIFORNIA INSTITUTE OF TECHNOLOGY · PI JACOBS, RUSSELL E · 2006 to 2010
$1.8M
Using Transport to Map the BrainR01NS062184 · NINDS · UNIVERSITY OF NEW MEXICO · PI BEARER, ELAINE L · 2009 to 2010
$1.5M
Molecular mechanisms of anterograde transportR01NS046810 · NINDS · BROWN UNIVERSITY · PI BEARER, ELAINE L · 2004 to 2007
$1.1M
NIDA NIH HHS R01 DA018184NIGMS NIH HHS P50 GM085273NIMH NIH HHS R01 MH096093NINDS NIH HHS R01 NS046810NINDS NIH HHS R01 NS062184
6 · The paper itself

Abstract

Magnetic resonance (MR) imaging provides a method to obtain anatomical information from the brain in vivo that is not typically available by optical imaging because of this organ's opacity. MR is nondestructive and obtains deep tissue contrast with 100-µm

Indexed as

AnimalsAutomation, LaboratoryBrainImaging, Three-DimensionalIntravital MicroscopyMagnetic Resonance ImagingMicecomputational analysis and preprocessingmagnetic resonance imaging (MRI)manganese-enhanced magnetic resonance imaging (MEMRI)mouse and rodent brainphenotyping brain anatomy

Identifiers

PMID28678440
PMCPMC6195809
OpenAlexW2725720397

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.