Evidence map›Paper›PMID 28678397›Full record

ArticleCurrent protocols in neuroscience2017

Multisite Electrophysiology Recordings in Mice to Study Cross-Regional Communication During Anxiety.

Alexander Z Harris, Danielle Golder, Ekaterina Likhtik

Abstract read
In one paragraph

Article in Current protocols in neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Alexander Z HarrisDepartment of Psychiatry, Columbia University Medical Center, New York City, New York.
Danielle GolderDepartment of Biological Sciences, Hunter College, CUNY, New York City, New York.
Ekaterina LikhtikDepartment of Biological Sciences, Hunter College, CUNY, New York City, New York.

Funding

NMDA Receptor Hypofunction in the Amygdala of Schizophrenia PatientsP50MH096891 · NIMH · UNIVERSITY OF PENNSYLVANIA · PI GUR, RAQUEL E · 2012 to 2016
$10.6M
VTA-nucleus accumbens circuit dynamics underlying stress susceptibilityK08MH109735 · NIMH · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI HARRIS, ALEXANDER · 2017 to 2020
$793k
Modulation of fear and safety in the basal forebrain-amygdala-prefrontal networkK01MH105731 · NIMH · HUNTER COLLEGE · PI LIKHTIK, EKATERINA · 2015 to 2017
$495k
NIMH NIH HHS K01 MH105731NIMH NIH HHS K08 MH109735NIMH NIH HHS P50 MH096891
6 · The paper itself

Abstract

Recording neural activity in awake, freely moving mice is a powerful and flexible technique for dissecting the neural circuit mechanisms underlying pathological behavior. This unit describes protocols for designing a drive and recording single neurons and local field potentials during anxiety-related paradigms. We also include protocols for integrating pharmacologic and optogenetic means for circuit manipulations, which, when combined with electrophysiological recordings, demonstrate input-specific and cell-specific contributions to circuit-wide activity. We discuss the planning, execution, and troubleshooting of physiology experiments during anxiety-like behavior. © 2017 by John Wiley & Sons, Inc.

Indexed as

Action PotentialsAnimalsAnxietyCell CommunicationElectrodes, ImplantedElectrophysiologyMiceNerve NetNeuronsOptogeneticsWakefulnessanxietyimplant constructionimplant designin vivo electrophysiologylocal field potentialsmultisite recordings

Identifiers

PMID28678397
PMCPMC5783183

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.