ArticleNeurosciences (Riyadh, Saudi Arabia)2017
Neuropsychiatric and neurological problems among Vitamin B12 deficient young vegetarians.
Article in Neurosciences (Riyadh, Saudi Arabia), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.
- Hallucinations and Vitamin B12 Deficiency: A Systematic Review.Psychopathology · 2024Pooled it
- An Increase of Adropin Can Predict Depression Improvement.Nutrients · 2025Article
- Dietary changes as a risk factor and remedy for meditation-related challenges.Frontiers in nutrition · 2025Article
- The Role of Water-Soluble Vitamins and Vitamin D in Prevention and Treatment of Depression and Seasonal Affective Disorder in Adults.Nutrients · 2024Review
- Impact of vegetarianism on cognition and neuropsychological status among urban community-dwelling adults in Telangana, South India: a cross-sectional study.European journal of nutrition · 2024Article
- Vitamin B12 deficiency and neuropsychiatric symptoms in Lebanon: A cross-sectional study of vegans, vegetarians, and omnivores.PloS one · 2024Article
- Is Increasing Diet Diversity of Animal-Source Foods Related to Better Health-Related Quality of Life among Chinese Men and Women?Nutrients · 2023Article
- Review
- Targeting DNA Methylation in the Adult Brain through Diet.Nutrients · 2021Review
- Impaired Quality of Life in Patients with Autoimmune Atrophic Gastritis.Digestive diseases and sciences · 2021Observational
- Nutrition and behavioral health disorders: depression and anxiety.Nutrition reviews · 2021Review
- Review
- Vitamin BJournal of nutritional science · 2019Article
- Methylmalonic Acid Levels and their Relation with Cobalamin Supplementation in Spanish Vegetarians.Plant foods for human nutrition (Dordrecht, Netherlands) · 2018Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the frequency of neuropsychiatric and neurological problems in apparently healthy young vegetarians and estimate serum Vitamin B12, methylmalonic acid (MMA), and folic acid levels.
methodsThis prospective study was conducted in the Department of Biochemistry, Basic Medical Sciences Institute (BMSI), Jinnah Postgraduate Medical Center (JPMC), Karachi, Pakistan, in the years of 2012 and 2013. The data of 100 vegetarians and 100 omnivores were analyzed and compared.
resultsThe serum concentration of Vitamin B12 was significantly lower in the vegetarian group compared with the omnivore group (238+/-71 pg/ml vs. 401+/-170 pg/ml, p<0.001). In the vegetarian group, MMA level was significantly higher compared with the omnivores (285+/-89.4 nmol/L vs. 191+/-40.5 nmol/L, p<0.001). Regarding the neuropsychiatric and neurologic problems in the vegetarian group, the frequency of depression was 31% compared with 12% in the omnivore (p=0.002), paresthesias were 11% compared with 3% in the omnivores (p=0.04), peripheral neuropathy was 9% compared with 2% in the omnivores (p=0.05), psychosis was found in 11% subjects compared with 3% in the omnivores (p=0.04).
conclusionVegetarians have Vitamin B12 deficiency and are more prone to developing neuropsychiatric and neurological problems.
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Registered trials
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