Evidence map›Paper›PMID 28678189›Full record

ArticleNutrients2017

Reduction of Asthmatic Parameters by Sea Hare Hydrolysates in a Mouse Model of Allergic Asthma.

Ji Hyeon Ryu, Chengliang Xie, Eun-Jin Kim, Si-Hyang Park, Yeung Joon Choi, Sang Soo Kang, Min-Kyoung Shin, Dawon Kang

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ji Hyeon RyuDepartment of Convergence Medical Science, Gyeongsang National University, Jinju 52727, Korea. wlgus9217@naver.com.
Chengliang XieDepartment of Anatomy and Institute of Health Sciences, College of Medicine, Gyeongsang National University, Jinju 52727, Korea. xie830734@naver.com.
Eun-Jin KimDepartment of Physiology and Institute of Health Sciences, College of Medicine, Gyeongsang National University, Jinju 52727, Korea. eunjin1981@hanmail.net.
Si-Hyang ParkSunmarin Biotech, Tongyeong 53064, Korea. hyangi51@hanmail.net.
Yeung Joon ChoiDepartment of Seafood Science and Technology and Institute of Marine Industry, Gyeongsang National University, Tongyeong 53064, Korea. yjchoi@gnu.ac.kr.
Sang Soo KangDepartment of Anatomy and Institute of Health Sciences, College of Medicine, Gyeongsang National University, Jinju 52727, Korea. kangss@gnu.ac.kr.
Min-Kyoung ShinDepartment of Microbiology and Institute of Health Sciences, College of Medicine, Gyeongsang National University, Jinju 52727, Korea. mkshin@gnu.ac.kr.
Dawon KangDepartment of Convergence Medical Science, Gyeongsang National University, Jinju 52727, Korea. dawon@gnu.ac.kr.
Gyeongsang National University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sea hare has a variety of biological activities. However, little is known regarding the anti-asthmatic effects of sea hare. This study was performed to identify the effect of sea hare hydrolysates (SHH) on an ovalbumin (OVA)-induced allergic asthma model. The experimental asthma model was sensitized and challenged with OVA. We found that a high-dose of SHH (HSHH) significantly inhibited OVA-induced airway inflammation and mucus production around the airway in lung sections, while low- and medium-dose SHH showed an insignificant effect. In addition, HSHH highly reduced OVA-induced production of interleukin-4, -5, -13, leukotriene D4, E4, and histamine in bronchoalveolar lavage fluid. HSHH decreased the histamine-induced increase in the intracellular Ca

Indexed as

Animal FeedAnimalsAnti-Asthmatic AgentsAsthmaBody WeightBronchoalveolar Lavage FluidCell SurvivalDexamethasoneFemaleInvertebratesMiceMice, Inbred C57BLOvalbuminProtein HydrolysatesRandom AllocationAnti-Asthmatic AgentsDexamethasoneOvalbuminProtein Hydrolysatesairway smooth muscle cellasthmacytokinessea hare hydrolysates

Identifiers

PMID28678189
PMCPMC5537814
OpenAlexW2728077949

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.