ArticleJournal of neuro-oncology2017
A French retrospective study on clinical outcome in 102 choroid plexus tumors in children.
Article in Journal of neuro-oncology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
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Who cites it
25 citing papers in PubMed, 50 citations in OpenAlex.
- Overactivation of SHH signaling induces a cascade of dedifferentiation and oncogenesis in a new mouse model for choroid plexus carcinoma.Acta neuropathologica communications · 2026Article
- Giant cystic choroid plexus papilloma mimicking intracerebral hydatid cyst.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2026Article
- Report from the National Pediatric Cancer Foundation - infantile glioma and other non-embryonal central nervous system tumors: evolving molecular advances and current treatment landscape.Frontiers in oncology · 2026Review
- CPT-SIOP registry: evaluation of risk factors for disease progression in pediatric choroid plexus papilloma.Journal of neuro-oncology · 2025Article
- Choroid plexus tumors in adults: a retrospective mono-institutional study.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025Article
- Leptomeningeal Dissemination in Choroid Plexus Tumors: Magnetic Resonance Imaging Appearance and Risk Factors.Children (Basel, Switzerland) · 2025Article
- The composition of choroid plexus tumor research: a bibliometric analysis of the 100 most impactful studies to date.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2024Article
- Approaches to Minimise the Neurodevelopmental Impact of Choroid Plexus Carcinoma and Its Treatment.Life (Basel, Switzerland) · 2023Review
- Molecular heterogeneity of pediatric choroid plexus carcinomas determines the distinctions in clinical course and prognosis.Neuro-oncology · 2023Article
- Incidence and survival of choroid plexus tumors in the United States.Neuro-oncology practice · 2023Article
- Tumors of Choroid Plexus and Other Ventricular Tumors.Advances in experimental medicine and biology · 2023Article
- Final results of the Choroid Plexus Tumor study CPT-SIOP-2000.Journal of neuro-oncology · 2022Article
- Pre-operative embolization for staged treatment of infantile choroid plexus papilloma.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2022Article
- Article
- Infantile epileptic spasms syndrome as an initial presentation in infantile choroid plexus papilloma: A case report.Frontiers in pediatrics · 2022Article
- Paediatric atypical choroid plexus papilloma: is adjuvant therapy necessary?Journal of neuro-oncology · 2021Article
- The genetic landscape of choroid plexus tumors in children and adults.Neuro-oncology · 2021Article
- Synchronous choroid plexus papilloma and Wilms tumor in a girl, disclosing a Li-Fraumeni syndrome.Hereditary cancer in clinical practice · 2021Article
- Epigenetics impacts upon prognosis and clinical management of choroid plexus tumors.Journal of neuro-oncology · 2020Review
- Perinatal (fetal and neonatal) choroid plexus tumors: a review.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2019Review
Corrections and comments
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Authors and funding
18 authors at 11 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of this study was to review and describe therapeutic approaches in children with choroid plexus tumor (CPT) based on a nationwide series. The World Health Organization classification subdivides these rare tumors into three histological subtypes corresponding to three grades of malignancy: low grade (grade I) choroid plexus papilloma (CPP), intermediate grade (grade II) atypical choroid plexus papilloma (aCPP) and high grade (grade III) choroid plexus carcinoma (CPC). This retrospective study included 102 French children younger than 18 years, treated from 2000 to 2012: 54 CPP, 26 aCPP and 22 CPC. The 5 year overall survival was 100% in CPP, 96.2% in aCPP and 64.7% in CPC. In patients with localized disease, complete surgical resection was achieved in 48/52 CPP, 20/26 aCPP and 7/14 CPC. In this group, patients with complete surgical resection had better event free survival than patients with partial resection (88.9 vs. 41.6%). 28 patients (1 CPP, 6 aCPP and 22 CPC) had adjuvant chemotherapy. 2 aCPP and 9 CPC had radiotherapy. We underlined the need for a central histological review to accurately analyze clinical data; we reported a much higher overall survival for CPC than in most previous CPT series probably including atypical teratoid rhabdoid tumors. In our series, the 5 years overall survival in CPC (64.7%) was higher than event free survival (25.2%) and could be interpreted as a clue for the efficiency of adjuvant/salvage therapy even if the heterogeneity of applied treatments in this retrospective series does not allow for meaningful statistical comparisons.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.