Evidence map›Paper›PMID 28677055›Full record

ArticleEuropean radiology2017

Improved assessment of mediastinal and pulmonary pathologies in combined staging CT examinations using a fast-speed acquisition dual-source CT protocol.

Franziska M Braun, Veronica Holzner, Felix G Meinel, Marco Armbruster, Martina Brandlhuber, Birgit Ertl-Wagner, Wieland H Sommer

Abstract read
PubMed Publisher
In one paragraph

Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Franziska M BraunInstitute for Clinical Radiology, University Hospital Munich, Marchioninistraße 15, 81377, Munich, Germany. franziska.braun@med.uni-muenchen.de.
Veronica HolznerInstitute for Clinical Radiology, University Hospital Munich, Marchioninistraße 15, 81377, Munich, Germany.
Felix G MeinelInstitute for Clinical Radiology, University Hospital Munich, Marchioninistraße 15, 81377, Munich, Germany.
Marco ArmbrusterInstitute for Clinical Radiology, University Hospital Munich, Marchioninistraße 15, 81377, Munich, Germany.
Martina BrandlhuberInstitute for Clinical Radiology, University Hospital Munich, Marchioninistraße 15, 81377, Munich, Germany.
Birgit Ertl-WagnerInstitute for Clinical Radiology, University Hospital Munich, Marchioninistraße 15, 81377, Munich, Germany.
Wieland H SommerInstitute for Clinical Radiology, University Hospital Munich, Marchioninistraße 15, 81377, Munich, Germany.
München Klinik · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo demonstrate the feasibility of fast Dual-Source CT (DSCT) and to evaluate the clinical utility in chest/abdomen/pelvis staging CT studies.

methods45 cancer patients with two follow-up combined chest/abdomen/pelvis staging CT examinations (maximally ±10 kV difference in tube potential) were included. The first scan had to be performed with our standard protocol (fixed pitch 0.6), the second one using a novel fast-speed DSCT protocol (fixed pitch 1.55). Effective doses (ED) were calculated, noise measurements performed. Scan times were compared, motion artefacts and the diagnostic confidence rated in consensus reading.

resultsED for the standard and fast-speed scans was 9.1 (7.0-11.1) mSv and 9.2 (7.4-12.8) mSv, respectively (P = 0.075). Image noise was comparable (abdomen; all P > 0.05) or reduced for fast-speed CTs (trachea, P = 0.001; ascending aorta, P < 0.001). Motion artefacts of the heart/the ascending aorta (all P < 0.001) and breathing artefacts (P < 0.031) were reduced in fast DSCT. The diagnostic confidence for the evaluation of mediastinal (P < 0.001) and pulmonary (P = 0.008) pathologies was improved for fast DSCT.

conclusionsFast DSCT for chest/abdomen/pelvis staging CT examinations is performed within 2 seconds scan time and eliminates relevant intrathoracic motion/breathing artefacts. Mediastinal/pulmonary pathologies can thus be assessed with high diagnostic confidence. Abdominal image quality remains excellent. KEY POINTS: • Fast dual-source CT provides chest/abdomen/pelvis staging examinations within 2 seconds scan time. • The sevenfold scan time reduction eliminates relevant intrathoracic motion/breathing artefacts. • Mediastinal/pulmonary pathologies can now be assessed with high diagnostic confidence. • The coverage of the peripheral soft tissues is comparable to single-source CT. • Fast and large-volume oncologic DSCT can be performed with 9 mSv effective dose.

Indexed as

AdultAgedAntineoplastic Combined Chemotherapy ProtocolsCytarabineFeasibility StudiesFemaleHumansLung NeoplasmsMaleMediastinumMiddle AgedNeoplasmsPelvisRadiation DosageRadiography, AbdominalRadiography, ThoracicCytarabineThioguanineAbdomenDual-source computed tomographyOncologyPelvisThorax

Identifiers

PMID28677055
OpenAlexW2731843290

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.