Evidence map›Paper›PMID 28677052›Full record

ArticleEuropean radiology2017

The longitudinal effect of ejaculation on seminal vesicle fluid volume and whole-prostate ADC as measured on prostate MRI.

Tristan Barrett, James Tanner, Andrew B Gill, Rhys A Slough, James Wason, Ferdia A Gallagher

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in European radiology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05192252 (Correlation Between Seminal Vesicle Size and Duration of Sexual Abstinence), which is not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05192252 unknown statusnot on this mapstarted 2021, after this paper: background citation

Correlation Between Seminal Vesicle Size and Duration of Sexual Abstinence

TypeobservationalSponsorFondation Hôpital Saint-JosephRan2021 to 2023Enrolled250ConditionsSuspected Prostate Cancer
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Tristan BarrettDepartment of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, CB2 0QQ, UK. tb507@medschl.cam.ac.uk.
James TannerDepartment of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, CB2 0QQ, UK.
Andrew B GillDepartment of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, CB2 0QQ, UK.
Rhys A SloughDepartment of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, CB2 0QQ, UK.
James WasonMRC Biostatistics Unit, University of Cambridge, Cambridge, CB2 0QQ, UK.
Ferdia A GallagherDepartment of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, CB2 0QQ, UK.
University of Cambridge · GBAddenbrooke's Hospital · GB

Funding

Cancer Research UK 16465Medical Research Council MC_UP_1302/4Medical Research Council MC_UU_00002/6Medical Research Council MR/N028171/1
6 · The paper itself

Abstract

objectiveTo prospectively investigate the longitudinal effect of ejaculatory abstinence on MRI-measured seminal vesicle (SV) volume and whole-prostate ADC over consecutive days.

methods15 healthy male volunteers (mean 35.9 years, range 27-53) underwent 3-T MRI at baseline and 1, 2 and 3 days post-ejaculation. Prostate and SV volumes were derived by volume segmentation and whole-gland apparent diffusion coefficient (ADC) values calculated. A mixed-effects linear regression compared ADC values and prostate/seminal vesicle volumes in each volunteer between studies in a pairwise manner.

resultsAll subjects completed the four MRIs. Mean prostate volume was 22.45 cm

conclusionThe longitudinal effect of ejaculation on SV volume was demonstrated. Significant reductions in SV volume and whole-gland ADC were observed post-ejaculation, supporting a 3-day period of abstinence before prostate MRI. KEY POINTS: • Seminal vesicle volume significantly reduced 24 h post-ejaculation remaining reduced at day 2 • Seminal vesicle fluid volume significantly increased from day 1 to day 3 post-ejaculation • There was a significant reduction in whole-gland prostate ADC values day 1 post-ejaculation • 3-day abstinence from ejaculation is required to ensure maximal seminal vesicle distension.

Indexed as

AdultEjaculationFollow-Up StudiesHealthy VolunteersHumansMagnetic Resonance ImagingMaleMiddle AgedOrgan SizeProspective StudiesProstateSemenSeminal VesiclesEjaculationMRIPreparationProstateSeminal vesicles

Identifiers

PMID28677052
PMCPMC5674119
OpenAlexW2731852151

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.