Evidence map›Paper›PMID 28676966›Full record

ReviewCurrent psychiatry reports2017

Eating Disorders and the Intestinal Microbiota: Mechanisms of Energy Homeostasis and Behavioral Influence.

Elaine M Glenny, Emily C Bulik-Sullivan, Quyen Tang, Cynthia M Bulik, Ian M Carroll

Open access · greenAbstract readReview
In one paragraph

Review in Current psychiatry reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 3 pooled it
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 3 syntheses or guidelines pooled it, 62 citations in OpenAlex.

  1. Pooled it
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  6. Article
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  14. Review
  15. Binge eating disorder.Nature reviews. Disease primers · 2022
    Article
  16. Article
  17. Article
  18. Decoding the Role of Gut-Microbiome in the Food Addiction Paradigm.International journal of environmental research and public health · 2021
    Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Elaine M GlennyDepartment of Nutrition, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Emily C Bulik-SullivanDepartment of Medicine, Center for Gastrointestinal Biology and Disease, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Quyen TangDepartment of Medicine, Center for Gastrointestinal Biology and Disease, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Cynthia M BulikDepartment of Nutrition, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Ian M CarrollDepartment of Nutrition, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA. ian_carroll@med.unc.edu.
University of North Carolina at Chapel Hill · USKarolinska Institutet · SE

Funding

UNIV OF NORTH CAROLINA CLINICAL NUTRITION RESEARCH UNITP30DK056350 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SUSAN M. SMITH · 1999 to 2026
$31.6M
NUTRITION TRAINING PROGRAMT32DK007686 · NIDDK · UNIV OF NORTH CAROLINA CHAPEL HILL · PI BECK, MELINDA A., MAYER-DAVIS, ELIZABETH J · 1992 to 2022
$4.3M
Microbiome-mediated weight, anxiety, and stress dysregulation in anorexia nervosaR01MH105684 · NIMH · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CARROLL, IAN MICHAEL · 2015 to 2019
$3.9M
NIDDK NIH HHS P30 DK056350NIMH NIH HHS R01 MH105684
6 · The paper itself

Abstract

purpose of reviewWe reviewed and evaluated recently published scientific studies that explored the role of the intestinal microbiota in eating disorders. RECENT

findingsStudies have demonstrated that the intestinal microbiota is a contributing factor to both host energy homeostasis and behavior-two traits commonly disrupted in patients with eating disorders. To date, intestinal microbiota research in eating disorders has focused solely on anorexia nervosa (AN). Initial studies have reported an atypical intestinal microbial composition in patients with AN compared to healthy controls. However, the impact of these AN-associated microbial communities on host metabolism and behavior remains unknown. The intriguing pattern of findings in patients with AN encourages further investigation of the intestinal microbiota in eating disorders. Elucidating the specific role(s) of these microbial communities may yield novel ideas for augmenting current clinical therapies to promote weight gain, decrease gastrointestinal distress, and even reduce psychological symptomatology.

Indexed as

Gastrointestinal MicrobiomeFeeding and Eating DisordersGastrointestinal DiseasesHomeostasisHumansBrain-gut-microbiota axisEating disordersIntestinal microbiotaMetabolism

Identifiers

PMID28676966
PMCPMC5881382
OpenAlexW2727159549

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.