ArticleMediators of inflammation2017
Proinflammatory Cytokines IL-6 and TNF-
RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph
Article in Mediators of inflammation, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 61 papers.
0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed
4.5field-weighted citation impact, top 4% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 106 citations in OpenAlex.
- PBMC telomerase activity in depression and the response to electroconvulsive therapy.European archives of psychiatry and clinical neuroscience · 2021Trial
- Comparison of the clinical usefulness of CXCL-8 and conventional clinical tumor markers for gastric cancer diagnosis.Clinics (Sao Paulo, Brazil) · 2026Article
- The emerging role of fatty acids as key bioactive components of Ganoderma lucidum spore oil in alleviating tumor progression.Journal of natural medicines · 2026Review
- RETRACTION: Proinflammatory Cytokines IL-6 and TNF-α Increased Telomerase Activity through NF-κB/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells.Mediators of inflammation · 2026Article
- Integration of network pharmacology and molecular docking reveals the anti-inflammatory efficacy of formononetin in Huangqin decoction and experiment verification in DSS-induced zebrafish IBD model.BMC complementary medicine and therapies · 2025Article
- HPV-driven inflammatory pathways in ovarian carcinogenesis: molecular mechanisms and emerging therapeutic interventions.Journal of ovarian research · 2025Review
- Article
- Pathogenic role and therapeutic targets of nuclear factor-κB signaling pathway in cancer (Review).Oncology letters · 2025Review
- A novel bispecific antibody targeting TNF-α and IL-6 receptor as a potent immunotherapeutic agent for inflammation.Applied microbiology and biotechnology · 2025Article
- Targeting cytokine and chemokine signaling pathways for enhancing chemo-sensitivity in colorectal cancer.Cell communication and signaling : CCS · 2025Review
- Cellular senescence in cancer: from mechanism paradoxes to precision therapeutics.Molecular cancer · 2025Review
- Comprehensive Single-Cell RNA Atlas of Human Laryngeal Normal, Preneoplastic, and Tumorigenic States.Clinical cancer research : an official journal of the American Association for Cancer Research · 2025Article
- Shortening Leukocyte Telomere Length Associated With Elevated Blood Diabetes-Related Cardiovascular Risk Factor in Thai Adolescents.Food science & nutrition · 2025Article
- The Therapeutic Potential of Bombyx Batryticatus for Chronic Atrophic Gastritis Precancerous Lesions via the PI3K/AKT/mTOR Pathway Based on Network Pharmacology of Blood-Entering Components.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Sparstolonin B Suppresses Proliferation and Modulates Toll-like Receptor Signaling and Inflammatory Pathways in Human Colorectal Cancer Cells.Pharmaceuticals (Basel, Switzerland) · 2025Article
- Expression of LncRNAs in anterior capsule of lens in patients with pathologic myopia complicated with cataract.International ophthalmology · 2024Article
- Metabolic profiling, antimicrobial, anticancer, and in vitro and in silico immunomodulatory investigation of Aspergillus niger OR730979 isolated from the Western Desert, Egypt.International microbiology : the official journal of the Spanish Society for Microbiology · 2024Article
- Chemical Characterization and In Vitro Evaluation of Glucans from Fermentation-Produced Nutraceutical Bionutri-AR1Pharmaceutics · 2024Article
- Syntaxin6 contributes to hepatocellular carcinoma tumorigenesis via enhancing STAT3 phosphorylation.Cancer cell international · 2024Article
- The mechanism of NF-κB-TERT feedback regulation of granulosa cell apoptosis in PCOS rats.PloS one · 2024Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
- Retraction · 2026-01-09Concerns/Issues about Image · Duplication of/in Image · Euphemisms for Duplication · Investigation by Journal/Publisher · Unreliable Results and/or Conclusions · · see also: https://pubpeer.com/publications/F26738B524F3162E9E389DEA6C94E4
- Retracted
Authors and funding
8 authors at 2 institutions in 1 country.
Seyung S ChungDivision of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 East 120th street, Los Angeles, CA 90059, USA.ORCID 0000-0002-0034-7077
Yong WuDivision of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 East 120th street, Los Angeles, CA 90059, USA.ORCID 0000-0002-1698-0897
Quincy OkobiDivision of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 East 120th street, Los Angeles, CA 90059, USA.
Debbie AdekoyaDivision of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 East 120th street, Los Angeles, CA 90059, USA.
Mohammad AtefiDivision of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 East 120th street, Los Angeles, CA 90059, USA.
Orette ClarkeDivision of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 East 120th street, Los Angeles, CA 90059, USA.
Pranabananda DuttaDivision of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 East 120th street, Los Angeles, CA 90059, USA.
Jaydutt V VadgamaDivision of Cancer Research and Training, Department of Internal Medicine, Charles R. Drew University of Medicine and Science, 1731 East 120th street, Los Angeles, CA 90059, USA.
Charles R. Drew University of Medicine and Science · USUniversity of California, Los Angeles · US
Funding
Sustaining Faculty Development & Community EngagementS21MD000103 · NIMHD · CHARLES R. DREW UNIVERSITY OF MED &SCI · PI CARLISLE, DAVID M · 2001 to 2015
$73.9MWorkshop for Junior Biostatisticians in Health ResearchU54MD007598 · NIMHD · CHARLES R. DREW UNIVERSITY OF MED & SCI · PI Jaydutt V. Vadgama · 2012 to 2026
$60.0MUCLA Clinical and Translational Science InstituteUL1TR000124 · NCATS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI DUBINETT, STEVEN M. · 2012 to 2015
$57.0MSupporting African American Churches to Promote Cancer ScreeningU54CA143931 · NCI · CHARLES R. DREW UNIVERSITY OF MED & SCI · PI VADGAMA, JAYDUTT V. · 2009 to 2022
$19.7MThe CDU-Clinical Research Education and Career Development ProgramR25MD007610 · NIMHD · CHARLES R. DREW UNIVERSITY OF MED & SCI · PI Roberto Balbino Vargas · 2012 to 2026
$7.8MMechanisms behind hyperglycemia-associated breast cancer risk and progressionSC1CA200517 · NCI · CHARLES R. DREW UNIVERSITY OF MED & SCI · PI WU, YONG · 2015 to 2018
$1.4MNCATS NIH HHS UL1 TR000124NCI NIH HHS SC1 CA200517NCI NIH HHS U54 CA143931NIMHD NIH HHS R25 MD007610NIMHD NIH HHS S21 MD000103NIMHD NIH HHS U54 MD007598
Abstract
There are increasing evidences of proinflammatory cytokine involvement in cancer development. Here, we found that two cytokines, IL-6 and TNF-
Indexed as
Blotting, WesternChromatin ImmunoprecipitationColorectal NeoplasmsHT29 CellsHumansImmunoprecipitationInterleukin-6NF-kappa BSignal TransductionSTAT1 Transcription FactorSTAT3 Transcription FactorTelomeraseTumor Necrosis Factor-alphaWithanolidesInterleukin-6NF-kappa BSTAT1 protein, humanSTAT1 Transcription FactorSTAT3 Transcription FactorTelomeraseTumor Necrosis Factor-alphawithaferin AWithanolides
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.