Evidence map›Paper›PMID 28676687›Full record

ArticleScientific reports2017

Maternal HtrA3 optimizes placental development to influence offspring birth weight and subsequent white fat gain in adulthood.

Ying Li, Lois A Salamonsen, Jonathan Hyett, Fabricio da Silva Costa, Guiying Nie

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Study on the Correlation between the Levels of HtrA3 and TGF-Journal of healthcare engineering · 2022
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Ying LiCentre for Reproductive Health, Hudson Institute of Medical Research, Clayton, Victoria, Australia.
Lois A SalamonsenCentre for Reproductive Health, Hudson Institute of Medical Research, Clayton, Victoria, Australia.
Jonathan HyettCentral Clinical School, University of Sydney, Sydney, New South Wales, Australia.
Fabricio da Silva CostaDepartment of Obstetrics and Gynaecology, Monash University, Clayton, Victoria, Australia.
Guiying NieCentre for Reproductive Health, Hudson Institute of Medical Research, Clayton, Victoria, Australia. guiying.nie@hudson.org.au.
Hudson Institute of Medical Research · AUMonash University · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

High temperature requirement factor A3 (HtrA3), a member of the HtrA protease family, is highly expressed in the developing placenta, including the maternal decidual cells in both mice and humans. In this study we deleted the HtrA3 gene in the mouse and crossed females carrying zero, one, or two HtrA3-expressing alleles with HtrA3

Indexed as

Gene DeletionAdipose Tissue, WhiteAnimalsAnimals, NewbornBirth WeightBreedingFemaleFetal Growth RetardationHumansInfantInfant, NewbornMicePlacentationPregnancySerine EndopeptidasesHTRA3 protein, humanPRSP protein, mouseSerine Endopeptidases

Identifiers

PMID28676687
PMCPMC5496872
OpenAlexW2732100998

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.