ArticleInternational journal of obesity (2005)2017
Changes in telomere length 3-5 years after gastric bypass surgery.
Article in International journal of obesity (2005), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 20 citations in OpenAlex.
- The Impact of Weight Loss Secondary to Bariatric Surgery on Telomere Biology: A Narrative Review.Biomedicines · 2026Review
- Telomere length dynamics measured by flow-FISH in patients with obesity undergoing bariatric surgery.Scientific reports · 2023Article
- Telomere Length and Mitochondrial DNA Copy Number Variations in Patients with Obesity: Effect of Diet-Induced Weight Loss-A Pilot Study.Nutrients · 2022Article
- Measurement of Telomere Length for Longitudinal Analysis: Implications of Assay Precision.American journal of epidemiology · 2021Article
- Best (but oft-forgotten) practices: identifying and accounting for regression to the mean in nutrition and obesity research.The American journal of clinical nutrition · 2020Article
- Response to 'Regression to the mean, apparent data errors, and biologically extraordinary results'.International journal of obesity (2005) · 2018Article
- Regression to the mean, apparent data errors and biologically extraordinary results: letter regarding 'changes in telomere length 3-5 years after gastric bypass surgery'.International journal of obesity (2005) · 2018Article
- Bariatric Surgery and Precision Nutrition.Nutrients · 2017Review
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6 authors at 1 institution in 1 country.
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Abstract
Increased inflammation and oxidative stress associated with obesity can accelerate aging. Telomere length (TL) has the capacity to serve as an aging indicator at the cellular level. Obesity has a known association with shorter TL. This study evaluated TL of immune cells in a population of obese individuals who underwent gastric bypass surgery. Pre- and post-operative DNA samples were available for 50 subjects who had gastric bypass surgery. DNA was analyzed via quantitative polymerase chain reaction to determine TL. Changes in TL were evaluated by comparing TL at baseline to TL at 3-5 years post gastric bypass surgery. Sixty percent of the individuals in the study observed an increase in TL. Significant lengthening was observed for those with the shortest baseline TL (P=0.0011), but not for those with intermediate baseline TL (P=0.411) or longest baseline TL (P=0.207). Change in TL was negatively correlated with age and triglycerides but not correlated with weight loss induced by bariatric surgery. This study confirms that TL lengthening is observed post bariatric surgery and is the first to detect TL lengthening 3-5 years after surgery.
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