ArticleScientific reports2017
HLA-E Presents Glycopeptides from the Mycobacterium tuberculosis Protein MPT32 to Human CD8
Open access · goldAbstract read
In one paragraph
Article in Scientific reports, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 38 citations in OpenAlex.
- Role of Donor Unrestricted T Cells (DURTs) in TB Host Defense: Implications for Novel TB Vaccine Development.Vaccines · 2026Review
- The Expanding Role of HLA-E in Host Defense: A Target for Broadly Applicable Vaccines and Immunotherapies.Cells · 2025Review
- Enhanced Glycosylation Caused by Overexpression of Rv1002c in a Recombinant BCG Promotes Immune Response and Protects againstVaccines · 2024Article
- An HLA-E-targeted TCR bispecific molecule redirects T cell immunity against Mycobacterium tuberculosis.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Recombinant mycobacterial DNA-binding protein 1 with post-translational modifications boosts IFN-gamma production from BCG-vaccinated individuals' blood cells in combination with CpG-DNA.Scientific reports · 2024Article
- Antibodies against native proteins of Mycobacterium tuberculosis can detect pulmonary tuberculosis patients.Scientific reports · 2023Article
- Protective RNA nanovaccines againstFrontiers in immunology · 2023Article
- MR1- and HLA-E-Dependent Antigen Presentation ofInternational journal of molecular sciences · 2022Review
- Antigen presentation by MHC-E: a putative target for vaccination?Trends in immunology · 2022Review
- Structure-guided stabilization of pathogen-derived peptide-HLA-E complexes using non-natural amino acids conserves native TCR recognition.European journal of immunology · 2022Article
- Structural aspects of chemical modifications in the MHC-restricted immunopeptidome; Implications for immune recognition.Frontiers in chemistry · 2022Review
- A Peptidomic Approach to Identify Novel Antigen Biomarkers for the Diagnosis of Tuberculosis.Infection and drug resistance · 2022Article
- The role of donor-unrestricted T-cells, innate lymphoid cells, and NK cells in anti-mycobacterial immunity.Immunological reviews · 2021Review
- Peptide Binding to HLA-E Molecules in Humans, Nonhuman Primates, and Mice Reveals Unique Binding Peptides but Remarkably Conserved Anchor Residues.Journal of immunology (Baltimore, Md. : 1950) · 2020Article
- T Cell Immunity to Bacterial Pathogens: Mechanisms of Immune Control and Bacterial Evasion.International journal of molecular sciences · 2020Review
- Does Antigen Glycosylation Impact the HIV-Specific T Cell Immunity?Frontiers in immunology · 2020Article
- Cross-validation of existing signatures and derivation of a novel 29-gene transcriptomic signature predictive of progression to TB in a Brazilian cohort of household contacts of pulmonary TB.Tuberculosis (Edinburgh, Scotland) · 2020Observational
- Tuberculosis Vaccine Development: Progress in Clinical Evaluation.Clinical microbiology reviews · 2019Review
- Impacts of the MHC class I-like XNC10 and innate-like T cells on tumor tolerance and rejection in the amphibian Xenopus.Carcinogenesis · 2019Article
- Mycobacterium smegmatis HtrA Blocks the Toxic Activity of a Putative Cell Wall Amidase.Cell reports · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 3 institutions in 1 country.
Melanie J HarriffVeterans Administration Portland Health Care System, Research & Development, 3710 SW US Veterans Hospital Road, Portland, OR, 97239, USA. harriffm@ohsu.edu.
Lisa M WolfeColorado State University, Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, 1682 Campus Delivery, Fort Collins, CO 80523, USA.
Gwendolyn SwarbrickOregon Health & Sciences University, Department of Pediatrics, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
Megan NullOregon Health & Sciences University, Department of Pediatrics, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
Meghan E CanslerOregon Health & Sciences University, Department of Pediatrics, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
Elizabeth T CanfieldOregon Health & Sciences University, Department of Pulmonary and Critical Care Medicine, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
Todd VogtOregon Health & Sciences University, Department of Pulmonary and Critical Care Medicine, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
Katelynne Gardner TorenOregon Health & Sciences University, Department of Pulmonary and Critical Care Medicine, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
Wei LiColorado State University, Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, 1682 Campus Delivery, Fort Collins, CO 80523, USA.
Mary JacksonColorado State University, Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, 1682 Campus Delivery, Fort Collins, CO 80523, USA.
Deborah A LewinsohnOregon Health & Sciences University, Department of Pediatrics, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.
Karen M DobosColorado State University, Mycobacteria Research Laboratories, Department of Microbiology, Immunology, and Pathology, 1682 Campus Delivery, Fort Collins, CO 80523, USA.
David M LewinsohnVeterans Administration Portland Health Care System, Research & Development, 3710 SW US Veterans Hospital Road, Portland, OR, 97239, USA. lewinsod@ohsu.edu.
Oregon Health & Science University · USColorado State University · USVA Portland Health Care System · US
Funding
Multidisciplinary Research Training in Pulmonary MedicineT32HL083808 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M., SLATORE, CHRISTOPHER G. · 2008 to 2025
$5.3MRecognition of Mtb-infected Cells by CD8+ T LymphocytesR01AI048090 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M. · 2001 to 2016
$4.2MRecognition of Mtb-Infected Cells by Non-Classically Restritcted CD8+ T CellsI01BX000533 · VA · PORTLAND VA MEDICAL CENTER · PI LEWINSOHN, DAVID M. · 2011 to 2024
–BLRD VA I01 BX000533CSRD VA IK2 CX000538NHLBI NIH HHS T32 HL083808NIAID NIH HHS R01 AI048090
Abstract
Infection with Mycobacterium tuberculosis (Mtb), the bacterium that causes tuberculosis, remains a global health concern. Both classically and non-classically restricted cytotoxic CD8
Indexed as
A549 CellsAntigen PresentationAntigens, BacterialCD8-Positive T-LymphocytesEpitopes, T-LymphocyteGlycopeptidesHEK293 CellsHistocompatibility Antigens Class IHLA-E AntigensHumansMannoseMycobacterium tuberculosisProtein Processing, Post-TranslationalTuberculosisAntigens, BacterialEpitopes, T-LymphocyteGlycopeptidesHistocompatibility Antigens Class IHLA-E AntigensMannose
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.