Evidence map›Paper›PMID 28676037›Full record

ArticleBMC nephrology2017

Challenges and outcomes of haemodialysis among patients presenting with kidney diseases in Dodoma, Tanzania.

Alfred J Meremo, David P Ngilangwa, Masumbuko Y Mwashambwa, Matobogolo B Masalu, Janet Kapinga, Rehema Tagalile, Issa Sabi

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03988491 (Predicting Morbidity, Mortality, Short and Long-term Survival of End-stage Kidney Disease Patients on Hemodialysis in Central Tanzania; a Two-center Prospective Patient-registry Observational Study.), which is not on this map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03988491 unknown statusnot on this mapstarted 2020, after this paper: background citation

Predicting Morbidity, Mortality, Short and Long-term Survival of End-stage Kidney Disease Patients on Hemodialysis in Central Tanzania; a Two-center Prospective Patient-registry Observational Study.

Typeobservational_patient_registrySponsorBenjamin Mkapa HospitalRan2020 to 2025Enrolled10,000ConditionsEnd-Stage Renal Disease
3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Alfred J MeremoSchool of Medicine & Dentistry, College of Health Sciences, The University of Dodoma, P.O Box 395, Dodoma, Tanzania.
David P NgilangwaAmref Health Africa, P.O Box 2773, Dar es Salaam, Tanzania.
Masumbuko Y MwashambwaSchool of Medicine & Dentistry, College of Health Sciences, The University of Dodoma, P.O Box 395, Dodoma, Tanzania.
Matobogolo B MasaluSchool of Medicine & Dentistry, College of Health Sciences, The University of Dodoma, P.O Box 395, Dodoma, Tanzania.
Janet KapingaHaemodialysis Unit, The University of Dodoma, P.O Box 259, Dodoma, Tanzania.
Rehema TagalileHaemodialysis Unit, The University of Dodoma, P.O Box 259, Dodoma, Tanzania.
Issa SabiNational Institute for Medical Research, Mbeya Medical Research Centre, P.O Box 2410, Mbeya, Tanzania. isabi@nimr-mmrc.org.ORCID http://orcid.org/0000-0002-1777-6572
The University of Dodoma · TZAmref Health Africa · TZNational Institute for Medical Research · TZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundKidney Diseases contribute a significant proportion to the global burden of non-communicable diseases. Haemodialysis services as the main modality of renal replacement therapy in most resource limited countries is only available in few cities and at higher costs. The aim of this study was to determine the challenges and outcomes of patients who were on haemodialysis at the University of Dodoma (UDOM) haemodialysis unit in Tanzania.

methodsIn this retrospective study; we reviewed haemodialysis registers and charts of 116 patients dialyzed from January 2013 to June 2015 at The UDOM haemodialysis unit. Data were descriptively and inferentially analysed using Stata version 11 software.

resultsOf the 116 patients, 52 (44.9%) were male, and 38(32.8%) were married. Their median age was 45 years. Thirty-two (27.6%) had acute kidney injury, of them 26 (81.3%) patients had recovery of renal function after haemodialysis. Indications for hemodialysis were anuria (18), intoxications (14), electrolyte imbalance (9), uraemia (7) infections (6) and fluid overload (4). Eighty-four (72.4%) patients had End Stage Renal Diseases (ESRD), of which 37 (44.1%) absconded/lost to follow up, 15 (17.9%) died, 22 (26.2%) were referred to Muhimbili National Hospital (MNH), 12 for possible kidney transplant abroad after haemodialysis, and 10 (11.9%) were still attending our unit for haemodialysis. Residing outside Dodoma was predictive for poor outcomes while on haemodialysis (OR 5.2, 95% CI 3.2-8.6, p < 0.001). In addition the odds ratio for poor outcomes was 7.3 times for a patient ESRD (OR7.34, 95% CI 3.26-18.17, p < 0.001). Patients who had no National Health Insurance Fund (NHIF) coverage (OR 6.6, 95% CI 5.4-12.7, p < 0.001) also had higher odds of poor outcomes after starting haemodialysis.

conclusionUnavailability and high costs related to utilization of haemodialysis services among patients needing dialysis are the challenges for better outcomes. Therefore, haemodialysis and renal transplants services should be made easily available in regional referral hospitals at reasonable costs. In addition, members of the public should be educated on joining health insurance schemes and on making healthy life style choices for preventing chronic kidney disease and its progression.

Indexed as

AdolescentAdultAgedChildFemaleHumansKidney Failure, ChronicMaleMiddle AgedRenal DialysisRetrospective StudiesSecondary Care CentersTanzaniaTreatment OutcomeYoung AdultChallengesChronic kidney diseases (CKD)HaemodialysisOutcomesTanzania

Identifiers

PMID28676037
PMCPMC5496638
OpenAlexW2732996648

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.