ArticlePharmaceutical biology2017
Protective mechanism of turmeric (Curcuma longa) on carbofuran-induced hematological and hepatic toxicities in a rat model.
Article in Pharmaceutical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 46 citations in OpenAlex.
- Supplementation with Curcuma longa Reverses Neurotoxic and Behavioral Damage in Models of Alzheimer's Disease: A Systematic Review.Current neuropharmacology · 2019Pooled it
- Trial
- Trial
- Curcumin Supplementation Mitigates Oxytetracycline-Induced Hematological, Immunological, and Oxidative Stress in Rainbow Trout (Veterinary sciences · 2026Article
- RETRACTION:Evidence-based complementary and alternative medicine : eCAM · 2026Article
- RETRACTION: Satkara (Evidence-based complementary and alternative medicine : eCAM · 2026Article
- Integrated metabolomics and mass spectrometry imaging reveal the Anti-Alzheimer's mechanisms of turmeric and curcumin.Frontiers in cell and developmental biology · 2026Article
- Review
- The potential liver injury induced by metronidazole-provoked disturbance of gut microbiota: modulatory effect of turmeric supplementation.Naunyn-Schmiedeberg's archives of pharmacology · 2024Article
- Assessment of the toxic influence of locally formulated pesticides on hepatic and renal biomarkers in male Wistar rats.Toxicology research · 2024Article
- Turmeric Extract-loaded Selenium Nanoparticles Counter Doxorubicin-induced Hepatotoxicity in MiceAnti-cancer agents in medicinal chemistry · 2024Article
- Role of nutraceutical against exposure to pesticide residues: power of bioactive compounds.Frontiers in nutrition · 2024Review
- Coenzyme Q10 ameliorates carbofuran induced hepatotoxicity and nephrotoxicity in wister rats.Heliyon · 2023Article
- Carbofuran pesticide toxicity to the eye.Experimental eye research · 2023Review
- Ameliorative mechanisms of turmeric-extracted curcumin on arsenic (As)-induced biochemical alterations, oxidative damage, and impaired organ functions in rats.Environmental science and pollution research international · 2021Article
- Antioxidant mediated protective effect ofToxicology reports · 2021Article
- Curcumin-loaded cockle shell-derived calcium carbonate nanoparticles: A novel strategy for the treatment of lead-induced hepato-renal toxicity in rats.Saudi journal of biological sciences · 2020Article
- Preclinical Evidence ofEvidence-based complementary and alternative medicine : eCAM · 2020Review
- The effects of laser diode treatment on liver dysfunction ofJournal of advanced veterinary and animal research · 2019Article
- Liver-targeted delivery of liposome-encapsulated curcumol using galactosylated-stearate.Experimental and therapeutic medicine · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextTurmeric (Curcuma longa L. [Zingiberaceae]) is used in the treatment of a variety of conditions including pesticide-induced toxicity.
objectiveThe study reports the antioxidant properties and the protective effects of turmeric against carbofuran (CF)-induced toxicity in rats. MATERIALS AND
methodsThe antioxidant potential was determined by using free radicals scavenging activity and ferric reducing antioxidant power values. Male Wistar rats were randomly divided into four groups, designated as control, turmeric (100 mg/kg/day), CF (1 mg/kg/day) and turmeric (100 mg/kg/day) + CF (1 mg/kg/day) treatments. All of the doses were administered orally for 28 consecutive days. The biological activity of the turmeric and CF was determined by using several standard biochemical methods.
resultsTurmeric contains high concentrations of polyphenols (8.97 ± 0.15 g GAEs), flavonoids (5.46 ± 0.29 g CEs), ascorbic acid (0.06 ± 0.00 mg AEs) and FRAP value (1972.66 ± 104.78 μM Fe DISCUSSION AND
conclusionTurmeric supplementation could protect against CF-induced hematological perturbations and hepatic injuries in rats, plausibly by the up-regulation of antioxidant enzymes and inhibition of LPO to confer the protective effect.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.