Evidence map›Paper›PMID 28675230›Full record

ArticleNanoscale2017

One-pot synthesis of nanochain particles for targeting brain tumors.

V S Perera, G Covarrubias, M Lorkowski, P Atukorale, A Rao, S Raghunathan, R Gopalakrishnan, B O Erokwu, Y Liu, D Dixit and 6 more

Open access · greenAbstract read
In one paragraph

Article in Nanoscale, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. PTPmu-targeted nanoparticles label invasive pediatric and adult glioblastoma.Nanomedicine : nanotechnology, biology, and medicine · 2020
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 1 country.

V S PereraDepartment of Biomedical Engineering, Case Western Reserve University, 1900 Euclid Avenue, Cleveland, 44139 Ohio, USA. stathis@case.edu.
G Covarrubias
M Lorkowski
P Atukorale
A Rao
S Raghunathan
R Gopalakrishnan
B O Erokwu
Y Liu
D Dixit
S M Brady-Kalnay
D Wilson
C Flask
J Rich
P M Peiris
E Karathanasis
Case Comprehensive Cancer CenterCase Western Reserve University · USCleveland Clinic · USCleveland Clinic Lerner College of Medicine · US

Funding

Interdisciplinary Biomedical Imaging Training ProgramT32EB007509 · NIBIB · CASE WESTERN RESERVE UNIVERSITY · PI DAVID Lynn WILSON, Xin Yu · 2007 to 2026
$5.6M
Treatment of glioblastoma using targeted nanoparticlesU01CA198892 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI KARATHANASIS, EFSTATHIOS · 2015 to 2019
$3.1M
Detection of micrometastasis using a dual-ligand nanoparticleR01CA177716 · NCI · CASE WESTERN RESERVE UNIVERSITY · PI KARATHANASIS, EFSTATHIOS · 2013 to 2017
$1.6M
NCI NIH HHS R01 CA177716NCI NIH HHS U01 CA198892NIBIB NIH HHS T32 EB007509
6 · The paper itself

Abstract

To synthesize multi-component nanochains, we developed a simple 'one-pot' synthesis, which exhibited high yield and consistency. The nanochains particles consist of parent nanospheres chemically linked into a higher-order, chain-like assembly. The one-pot synthesis is based on the addition of two types of parent nanospheres in terms of their surface chemical functionality (e.g., decorated with PEG-NH

Indexed as

AnimalsBrain NeoplasmsFerric CompoundsGlioblastomaGliomaMiceMice, NudeNanospheresFerric Compoundsferric oxide

Identifiers

PMID28675230
PMCPMC5557407
OpenAlexW2725823577

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.