Evidence map›Paper›PMID 28674870›Full record

Trial reportClinical autonomic research : official journal of the Clinical Autonomic Research Society2017

Heart-rate response to alpha

David D Kim, Donna J Lang, Darren E R Warburton, Melissa L Woodward, Randall F White, Alasdair M Barr, William G Honer, Ric M Procyshyn

Registry-linked trialAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01392885 (Brain Health), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01392885 recruitingnot on this map

Brain Health: Effects of Exercise on Hippocampal Volume and Memory Deficits in Persons With Schizophrenia

TypeobservationalSponsorBC Mental Health and Addictions Research InstituteRan2011 to 2026Enrolled60ConditionsSchizophrenia, Schizoaffective Disorder, Poor Memory
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

David D KimDepartment of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, Canada.
Donna J LangDepartment of Radiology, University of British Columbia, Vancouver, BC, Canada.
Darren E R WarburtonCardiovascular Physiology and Rehabilitation Laboratory, Physical Activity Promotion and Chronic Disease Prevention Unit, University of British Columbia, Vancouver, BC, Canada.
Melissa L WoodwardDepartment of Radiology, University of British Columbia, Vancouver, BC, Canada.
Randall F WhiteDepartment of Psychiatry, University of British Columbia, Room A3-111, 938 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.
Alasdair M BarrDepartment of Anesthesiology, Pharmacology and Therapeutics, University of British Columbia, Vancouver, BC, Canada.
William G HonerDepartment of Psychiatry, University of British Columbia, Room A3-111, 938 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada.
Ric M ProcyshynDepartment of Psychiatry, University of British Columbia, Room A3-111, 938 West 28th Avenue, Vancouver, BC, V5Z 4H4, Canada. rprocyshyn@bcmhs.bc.ca.ORCID http://orcid.org/0000-0002-4348-0855
University of British Columbia · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo explore the relationship between antipsychotic-associated antagonism of alpha

methodsThirty-one inpatients treated with antipsychotics were included in this exploratory analysis. Antipsychotic doses were converted to haloperidol equivalents for alpha

resultsAfter controlling for confounding variables, the relationship between alpha

conclusionThe observed inverted-U relationship between alpha GOV IDENTIFIER: NCT01392885.

Indexed as

Adrenergic alpha-2 Receptor AntagonistsAdultAntipsychotic AgentsFemaleHeart RateHumansMalePsychotic DisordersSchizophreniaAdrenergic alpha-2 Receptor AntagonistsAntipsychotic AgentsAlpha2-adrenergic receptorsAntipsychoticsHeart rateSchizophrenia

Identifiers

PMID28674870
OpenAlexW2728309003

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.