Evidence map›Paper›PMID 28674735›Full record

ArticleInternational urogynecology journal2018

Reoperation for pelvic organ prolapse: a Danish cohort study with 15-20 years' follow-up.

Ea Løwenstein, Lars Alling Møller, Jennie Laigaard, Helga Gimbel

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in International urogynecology journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06363903 (Autoimmume/Inflammatory Syndrome Induced by Adjuvants), which is not on this map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.8field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06363903 unknown statusnot on this mapstarted 2022, after this paper: background citation

Autoimmume/Inflammatory Syndrome Induced by Adjuvants (ASIA Syndrome) Caused by Polypropylene Mesh Implantation - a Pilot Study for Diagnostics and Treatment

TypeobservationalSponsorMaxima Medical CenterRan2022 to 2025Enrolled50ConditionsAutoimmunity, Inguinal Hernia, Stress Urinary Incontinence, Pelvic Organ ProlapseArmsmesh allergy test, blood tests, Mesh removal
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 46 citations in OpenAlex.

  1. Trial
  2. Ten Years of Laparoscopic Pectopexy: A Case Series Analysis.International urogynecology journal · 2026
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  16. Timing of recurrence after surgery in pelvic organ prolapse.International urogynecology journal · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ea LøwensteinDepartment of Obstetrics and Gynecology, Nykøbing Falster Hospital, Nykøbing Falster, Denmark. ea.loewenstein@gmail.com.ORCID http://orcid.org/0000-0002-7358-7661
Lars Alling MøllerDepartment of Obstetrics and Gynecology, Zealands University Hospital, Roskilde, Denmark.
Jennie LaigaardDepartment of Obstetrics and Gynecology, Zealands University Hospital, Roskilde, Denmark.
Helga GimbelDepartment of Obstetrics and Gynecology, Nykøbing Falster Hospital, Nykøbing Falster, Denmark.
Sjællands Universitetshospital, Nykøbing F. · DKZealand University Hospital · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisThe objectives were to determine the reoperation rate of primary pelvic organ prolapse (POP) surgery, to describe the age distribution of the women at primary surgery for those undergoing a reoperation, and to describe the incidence of second and third reoperations.

methodsWe carried out a population-based registry study of Danish women above the age of 18 years when undergoing primary surgery for POP during the period 1996-2000. Data were retrieved from the Danish National Patient Register. All women were followed until one of the following events occurred: reoperation for POP, death, emigration, or end of follow-up period. Reoperation was defined as "repeated surgery in same compartment". The cumulative incidence rate of reoperation was divided into three compartments (anterior, apical, and posterior) and was calculated using Kaplan-Meier plots.

resultsA total of 18,382 procedures were performed on 11,805 women. After 20 years' follow-up, the cumulated incidence rate of reoperation for POP in the anterior, apical, and posterior compartments was 12.4%, 7.9%, and 12.1% respectively. The overall rate of reoperation was 11.5%. Of women aged between 18 and 49 years of age at primary surgery, 26.9% had a reoperation, whereas in women between 50 and 90+ years of age at primary surgery, only 10.1% had a reoperation.

conclusionsThis large study with up to 20 years' follow-up has found that reoperation for POP is modest, that the reoperation rate is lowest for the apical compartment, but highest in all three compartments during the first year after primary surgery. The reoperation rate peaks in the group of women who had their primary surgery before the menopause in all three compartments.

Indexed as

Age DistributionAge FactorsDenmarkFemaleFollow-Up StudiesGynecologic Surgical ProceduresHumansIncidencePelvic Organ ProlapseRecurrenceRegistriesReoperationRisk FactorsCompartmentPelvic organ prolapseRecurrenceReoperationRepeated surgeryWomen

Identifiers

PMID28674735
OpenAlexW2733351598

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.