Evidence map›Paper›PMID 28674624›Full record

ArticleOpen heart

Left atrial strain predicts recurrence of atrial arrhythmias after catheter ablation of persistent atrial fibrillation.

Abdul Shokor Parwani, Daniel-Armando Morris, Florian Blaschke, Martin Huemer, Burkert Pieske, Wilhelm Haverkamp, Leif-Hendrik Boldt

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Open heart. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03962166 active not recruitingnot on this map

Characterizing Patients With Post-operative Atrial Fibrillation in Relation to Cardiac Surgery by Signal Processed Surface Electrocardiogram (wavECG) and Transthoracic Echocardiography A LAACS-2 Sub-study

TypeobservationalSponsorHelena DOMINGUEZRan2019 to 2026Enrolled353ConditionsAtrial Fibrillation, Left Ventricular Diastolic Dysfunction
NCT06417112 completednot on this map

Can Left Atrial Strain Measurements, and Correlating Changes in Left Atrium Area and Volume Size, be Used as an Early Predictor of Atrial Fibrillation?

TypeobservationalSponsorHywel Dda Health BoardRan2023 to 2024Enrolled72ConditionsAtrial Fibrillation, HypertensionArmsTransthoracic Echocardiogram
3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Abdul Shokor ParwaniDepartment of Cardiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Daniel-Armando MorrisDepartment of Cardiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Florian BlaschkeDepartment of Cardiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Martin HuemerDepartment of Cardiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Burkert PieskeDepartment of Cardiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Wilhelm HaverkampDepartment of Cardiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Leif-Hendrik BoldtDepartment of Cardiology, Charité - Universitätsmedizin Berlin, Berlin, Germany.
Charité - Universitätsmedizin Berlin · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSuccess rates of catheter ablation (CA) of persistent atrial fibrillation (AF) are very variable. Identifying patients in whom sinus rhythm maintenance cannot be achieved after CA is a critical issue.

methods2D speckle-tracking echocardiography was performed before the first CA procedure in consecutive patients with persistent AF. Left atrial (LA) strain was correlated with recurrence of atrial arrhythmias during the follow-up period of 15 months after one CA procedure with or without antiarrhythmic drugs (primary endpoint). In a secondary analysis, recurrences after two CA procedures were analysed.

results102 patients were included. Patients with recurrence of atrial arrhythmias after one CA procedure (n=55) had significantly lower LA strain than those without recurrence (LA strain 9.7±2.4% vs 16.2±3.0%; p<0.001). Recurrence rate was significantly higher in patients with LA strain <10% than in those with LA strain between 10% and 14.5% and >14.5% (97.7%, 42.1% and 10.3%, respectively; p<0.001). In Cox regression analysis including age, comorbidities, left ventricular dysfunction and LA enlargement, low LA strain (<10%) was the strongest factor associated with recurrence of AF (HR 6.4 (2.4-16.9), p<0.001). Even after inclusion of a second CA procedure, LA strain <10% maintained a high predictive value for recurrence of atrial arrhythmias (86.4% (95% CI 73.3% to 93.6%)).

conclusionIn patients with persistent AF, LA strain imaging could be very useful to select those patients who have a high risk of not benefiting from CA.

Indexed as

atrial fibrillationatrial fibrillation recurrencecatheter ablationleft atrial strain

Identifiers

PMID28674624
PMCPMC5471873
OpenAlexW2607980378

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.