ArticleOpen heart
The systolic paradox in hypertrophic cardiomyopathy.
Article in Open heart. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 41 citations in OpenAlex.
- Phenotypic Spectrum of Subclinical Sarcomere-Related Hypertrophic Cardiomyopathy and Transition to Overt Disease.Circulation. Genomic and precision medicine · 2024Pooled it
- Trial
- Assessment of right ventricular systolic function in patients with hypertrophic cardiomyopathy by layer-specific speckle tracking echocardiography.Quantitative imaging in medicine and surgery · 2026Article
- A multi-scale finite element method for investigating fiber remodeling in hypertrophic cardiomyopathy.Scientific reports · 2025Article
- A pilot study for risk stratification of ventricular tachyarrhythmia in hypertrophic cardiomyopathy with routine echocardiography parameters.Scientific reports · 2024Article
- Insights into the effects of Friedreich ataxia on the left ventricle using T1 mapping and late gadolinium enhancement.PloS one · 2024Article
- AnBioMed research international · 2024Article
- Fabry Disease: More than a Phenocopy of Hypertrophic Cardiomyopathy.Journal of clinical medicine · 2023Review
- Phenotyping heart failure by echocardiography: imaging of ventricular function and haemodynamics at rest and exercise.European heart journal. Cardiovascular Imaging · 2023Article
- Left atrial strain assessment using cardiac computed tomography in patients with hypertrophic cardiomyopathy.Japanese journal of radiology · 2023Article
- Microvascular Dysfunction Is Associated With Impaired Myocardial Work in Obstructive and Nonobstructive Hypertrophic Cardiomyopathy: A Multimodality Study.Journal of the American Heart Association · 2023Article
- Pressure-Strain Loops, a Novel Non-invasive Approach for Assessment of Children with Cardiomyopathy.Pediatric cardiology · 2022Article
- Right ventricular function declines prior to left ventricular ejection fraction in hypertrophic cardiomyopathy.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance · 2022Article
- Contemporary Diagnosis and Management of Hypertrophic Cardiomyopathy: The Role of Echocardiography and Multimodality Imaging.Journal of cardiovascular development and disease · 2022Review
- Critical Evaluation of Current Hypotheses for the Pathogenesis of Hypertrophic Cardiomyopathy.International journal of molecular sciences · 2022Review
- An Implementation of Patient-Specific Biventricular Mechanics Simulations With a Deep Learning and Computational Pipeline.Frontiers in physiology · 2021Article
- The role of echocardiography in management of hypertrophic cardiomyopathy.Journal of echocardiography · 2020Review
- Five-year prognostic significance of global longitudinal strain in individuals with a hypertrophic cardiomyopathy gene mutation without hypertrophic changes.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2019Article
- Left ventricular structural and functional changes in Friedreich ataxia - Relationship with body size, sex, age and genetic severity.PloS one · 2019Article
- Aortic annular plane systolic excursion in cats with hypertrophic cardiomyopathy.Journal of veterinary internal medicineArticle
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe explored cardiac volumes and the effects on systolic function in hypertrophic cardiomyopathy (HCM) patients with left ventricular hypertrophy (HCM LVH+) and genotype-positive patients without left ventricular hypertrophy (HCM LVH-).
methodsWe included 180 HCM LVH+, 100 HCM LVH- patients and 80 healthy individuals. End-Diastolic Volume Index (EDVI), End-Systolic Volume Index (ESVI) and ejection fraction (EF) were assessed by echocardiography. Left ventricular (LV) global longitudinal strain (GLS) was measured by speckle tracking echocardiography.
resultsEDVI and ESVI were significantly smaller in HCM LVH+ compared with HCM LVH- patients (41±14 mL/m
conclusionHCM LVH+ had smaller cardiac volumes that could explain the preserved EF, despite worse GLS that was closely related to MWT. HCM LVH- had reduced cardiac volumes and subtle changes in GLS compared with healthy individuals, indicating a continuum of both volumetric and systolic changes present before increased MWT.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.