Evidence map›Paper›PMID 28674519›Full record

ArticleFrontiers in endocrinology2017

Somatostatin-IRES-Cre Mice: Between Knockout and Wild-Type?

Cécile Viollet, Axelle Simon, Virginie Tolle, Alexandra Labarthe, Dominique Grouselle, Yann Loe-Mie, Michel Simonneau, Guillaume Martel, Jacques Epelbaum

Open access · goldAbstract read
In one paragraph

Article in Frontiers in endocrinology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 48 citations in OpenAlex.

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  10. GABAergic/Glycinergic and Glutamatergic Neurons Mediate Distinct Neurodevelopmental Phenotypes ofThe Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  11. Article
  12. Growth Hormone Action in Somatostatin Neurons Regulates Anxiety and Fear Memory.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Cécile ViolletINSERM U894, Centre de Psychiatrie et Neurosciences, Université Paris-Descartes, Sorbonne Paris-Cité, Paris, France.
Axelle SimonINSERM U894, Centre de Psychiatrie et Neurosciences, Université Paris-Descartes, Sorbonne Paris-Cité, Paris, France.
Virginie TolleINSERM U894, Centre de Psychiatrie et Neurosciences, Université Paris-Descartes, Sorbonne Paris-Cité, Paris, France.
Alexandra LabartheINSERM U894, Centre de Psychiatrie et Neurosciences, Université Paris-Descartes, Sorbonne Paris-Cité, Paris, France.
Dominique GrouselleINSERM U894, Centre de Psychiatrie et Neurosciences, Université Paris-Descartes, Sorbonne Paris-Cité, Paris, France.
Yann Loe-MieINSERM U894, Centre de Psychiatrie et Neurosciences, Université Paris-Descartes, Sorbonne Paris-Cité, Paris, France.
Michel SimonneauINSERM U894, Centre de Psychiatrie et Neurosciences, Université Paris-Descartes, Sorbonne Paris-Cité, Paris, France.
Guillaume MartelINSERM U894, Centre de Psychiatrie et Neurosciences, Université Paris-Descartes, Sorbonne Paris-Cité, Paris, France.
Jacques EpelbaumINSERM U894, Centre de Psychiatrie et Neurosciences, Université Paris-Descartes, Sorbonne Paris-Cité, Paris, France.
Délégation Paris 5 · FRUniversité Paris Cité · FRInserm · FRSorbonne Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The neuropeptide somatostatin (SOM) is widely expressed in rodent brain and somatostatin-IRES-Cre (SOM-cre) mouse strains are increasingly used to unravel the physiology of SOM-containing neurons. However, while knock-in targeting strategy greatly improves Cre-Lox system accuracy, recent reports have shown that genomic insertion of Cre construct

Indexed as

corticosteronecre micefeminizationgrowth hormone secretory patternshepatic expression

Identifiers

PMID28674519
PMCPMC5474965
OpenAlexW2642147666

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.