ArticleFrontiers in psychiatry2017
Antigliadin Antibodies (AGA IgG) Are Related to Neurochemistry in Schizophrenia.
Article in Frontiers in psychiatry, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Pooled it
- Randomized double-blind inpatient study of a gluten-free diet for negative symptoms in people with schizophrenia.Schizophrenia research · 2026Trial
- Pilot study indicates that a gluten-free diet lowers oxidative stress for gluten-sensitive persons with schizophrenia.Schizophrenia research · 2024Trial
- Randomized controlled trial of a gluten-free diet in patients with schizophrenia positive for antigliadin antibodies (AGA IgG): a pilot feasibility studyJournal of psychiatry & neuroscience : JPN · 2019Trial
- T cells are associated with negative symptoms in persons with anti-gliadin antibody positive schizophrenia and related disorders.Schizophrenia research · 2025Article
- Article
- Sex differences in abnormal gluten response and predictors of gluten sensitivity in patients with schizophrenia.Frontiers in immunology · 2025Article
- Microstructural and Microvascular Alterations in Psychotic Spectrum Disorders: A Three-Compartment Intravoxel Incoherent Imaging and Free Water Model.Schizophrenia bulletin · 2023Article
- The relationship of peripheral inflammation with antibodies to gliadin (AGA IgG) in persons with schizophrenia.Schizophrenia research · 2023Article
- The potential ofPsychopharmacology · 2021Review
- The Differences between Gluten Sensitivity, Intestinal Biomarkers and Immune Biomarkers in Patients with First-Episode and Chronic Schizophrenia.Journal of clinical medicine · 2020Article
- Examination of plasma zonulin levels in bipolar I disorder: a case-control study with follow-up.Journal of neural transmission (Vienna, Austria : 1996) · 2020Article
- Upregulation of the Intestinal Paracellular Pathway with Breakdown of Tight and Adherens Junctions in Deficit Schizophrenia.Molecular neurobiology · 2019Article
- Breakdown of the Paracellular Tight and Adherens Junctions in the Gut and Blood Brain Barrier and Damage to the Vascular Barrier in Patients with Deficit Schizophrenia.Neurotoxicity research · 2019Article
- Gut permeability and mimicry of the Glutamate Ionotropic Receptor NMDA type Subunit Associated with protein 1 (GRINA) as potential mechanisms related to a subgroup of people with schizophrenia with elevated antigliadin antibodies (AGA IgG).Schizophrenia research · 2019Article
- Proton magnetic resonance spectroscopy changes in a longitudinal schizophrenia study: a pilot study in eleven patients.Neuropsychiatric disease and treatment · 2019Article
- Autoimmune phenotypes in schizophrenia reveal novel treatment targets.Pharmacology & therapeutics · 2018Review
- Gliadin-related antibodies in schizophrenia.Schizophrenia research · 2018Article
- Anti gliadin antibodies (AGA IgG) related to peripheral inflammation in schizophrenia.Brain, behavior, and immunity · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 3 institutions in 1 country.
Funding
Abstract
Inflammation may play a role in schizophrenia; however, subgroups with immune regulation dysfunction may serve as distinct illness phenotypes with potential different treatment and prevention strategies. Emerging data show that about 30% of people with schizophrenia have elevated antigliadin antibodies of the IgG type, representing a possible subgroup of schizophrenia patients with immune involvement. Also, recent data have shown a high correlation of IgG-mediated antibodies between the periphery and cerebral spinal fluid in schizophrenia but not healthy controls, particularly AGA IgG suggesting that these antibodies may be crossing the blood-brain barrier with resulting neuroinflammation. Proton magnetic resonance spectroscopy (MRS) is a non-invasive technique that allows the quantification of certain neurochemicals
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.