Evidence map›Paper›PMID 28674363›Full record

ArticleInternal medicine (Tokyo, Japan)2017

EBV-positive Diffuse Large B-cell Lymphoma as a Secondary Malignancy Arising in a Myelodysplastic Syndrome Patient who Was Treated with Azacitidine.

Naruko Suzuki, Junji Hiraga, Hiroki Kato, Yusuke Takagi, Nobuko Ujihira, Michihiko Narita, Yoshitoyo Kagami

Abstract readCase Reports
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Naruko SuzukiDepartment of Hematology, Toyota Kosei Hospital, Japan.
Junji HiragaDepartment of Hematology, Toyota Kosei Hospital, Japan.
Hiroki KatoDepartment of Hematology, Toyota Kosei Hospital, Japan.
Yusuke TakagiDepartment of Hematology, Toyota Kosei Hospital, Japan.
Nobuko UjihiraDepartment of Pathology, Toyota Kosei Hospital, Japan.
Michihiko NaritaDepartment of Pathology, Toyota Kosei Hospital, Japan.
Yoshitoyo KagamiDepartment of Hematology, Toyota Kosei Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of secondary diffuse large B-cell lymphoma (DLBCL) after azacitidine (AZA) treatment in a 63-years-old man with myelodysplastic syndrome. The patient suffered from febrile neutropenia after 10 cycles of AZA treatment. Despite the performance of a whole-body CT scan, which showed a multifocal low-density area in the liver and a multifocal nodular shadow in the lung, no malignant neoplasms could be detected. An autopsy was performed 6 months later, and a histopathological examination of the lesions of the liver and lung revealed the infiltration of large round-shaped tumor cells with necrotizing lesions. Immunohistochemically, the tumor cells were positive for CD20 and EBER, indicating EBV-positive DLBCL as a secondary malignancy.

Indexed as

AzacitidineHumansLymphoma, Large B-Cell, DiffuseMaleMiddle AgedMyelodysplastic SyndromesNeoplasms, Second PrimaryAzacitidineazacitidinemyelodysplastic syndromesecondary malignancy

Identifiers

PMID28674363
PMCPMC5519476

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.