Evidence map›Paper›PMID 28674286›Full record

ArticleExperimental animals2017

Evaluation of a TPTX model induced by ischemia.

Haoran Yuan, Yongzhao Shi, Yinghua Li, Lin Yang, Yan Tang, Zhiqing Hu, Ran Du, Xueqing Li, Lingbin Gu, Hui Wang and 2 more

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Experimental animals, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Hypothyroidism Modeling in Wistar Rats: Comparison of Two Surgical Methods.Bulletin of experimental biology and medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Haoran YuanDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, 801 Heqing Road, Minhang District, Shanghai 200240, P.R. China.
Yongzhao ShiDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, 801 Heqing Road, Minhang District, Shanghai 200240, P.R. China.
Yinghua LiCentral Laboratory, The Fifth People's Hospital of Shanghai, Fudan University, 801 Heqing Road, Minhang District, Shanghai 200240, P.R. China.
Lin YangDepartment of Nephrology, The Fifth People's Hospital of Shanghai, Fudan University, 801 Heqing Road, Minhang District, Shanghai 200240, P.R. China.
Yan TangDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, 801 Heqing Road, Minhang District, Shanghai 200240, P.R. China.
Zhiqing HuDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, 801 Heqing Road, Minhang District, Shanghai 200240, P.R. China.
Ran DuDepartment of Oncology, The Fifth People's Hospital of Shanghai, Fudan University, 801 Heqing Road, Minhang District, Shanghai 200240, P.R. China.
Xueqing LiDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, 801 Heqing Road, Minhang District, Shanghai 200240, P.R. China.
Lingbin GuDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, 801 Heqing Road, Minhang District, Shanghai 200240, P.R. China.
Hui WangDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, 801 Heqing Road, Minhang District, Shanghai 200240, P.R. China.
Chenhui XiDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, 801 Heqing Road, Minhang District, Shanghai 200240, P.R. China.
Chenghui TangDepartment of General Surgery, The Fifth People's Hospital of Shanghai, Fudan University, 801 Heqing Road, Minhang District, Shanghai 200240, P.R. China.
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parathyroidectomy (PTX), especially total parathyroidectomy (TPTX), is often recommended for severe secondary hyperparathyroidism (SHPT) if other medical treatments fail. Accurate identification and resection of parathyroid gland (PTG) tissue is the cornerstone of PTX. The establishment of a rat TPTX model would be beneficial for several applications but faces the same problems. In this experiment, we studied the mechanisms of ischemia for the accurate identification and excision of PTG tissue to establish TPTX rat models and to analyze the effects of surgical removal of PTG tissue as well as the effects of different types of water intake in rats on clinical indices. We found that the ischemia method had advantages when establishing a rat TPTX model. Removal of the PTG tissue resulted in significantly changed postoperative indices, and varying the types of water intake induced significant differences in these indices after removal of the PTG tissue. The absolute value of the difference between the serum calcium and phosphorus concentrations (|Ca-P|) accurately reflected the effect of removal of the PTG tissue and was superior to the calcium-phosphorus product (Ca × P); Ca × P accurately reflected the effect of varying the types of water intake in rats and was superior to the |Ca-P|.

Indexed as

Disease Models, AnimalIschemiaAnimalsCalciumDrinkingHyperparathyroidism, SecondaryMaleParathyroidectomyParathyroid GlandsPhosphorusRats, Sprague-DawleySeverity of Illness IndexCalciumPhosphorus|Ca−P|Ca × PischemiaSHPTTPTX

Identifiers

PMID28674286
PMCPMC5682347
OpenAlexW2727787292

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.