Evidence map›Paper›PMID 28674238›Full record

ArticleJournal of genetics2017

Characterization of duck (Anas platyrhynchos) MHC class I gene in two duck lines.

Lin Zhang, Wei-Jie Liu, Jia-Qiang Wu, Min-Li Xu, Zheng-Jie Kong, Yan-Yan Huang, Shao-Hua Yang

Abstract read
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In one paragraph

Article in Journal of genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Lin ZhangInstitute of Animal Science and Veterinary Medicine, Shandong Academy of Agricultural Science/Shandong Key Lab of Animal Disease Control and Breeding, Jinan 250100, Shandong, People's Republic of China. 443794629@qq.com.
Wei-Jie Liu
Jia-Qiang Wu
Min-Li Xu
Zheng-Jie Kong
Yan-Yan Huang
Shao-Hua Yang
Shandong Academy of Agricultural Sciences · CNShandong Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To enrich gene polymorphism ofDuMHCI and provide data for further studies on disease resistance, 14DuMHCI genes from Weishan Ma duck and Cherry Valley duck were cloned, and their characterization were investigated. The overall conservation of the 14 alleles could be observed within the sequences, and relative conservation were also displayed in the peptide-binding domain and CD8 interaction sites. Based on full-length amino acid homology, MHC class I from different duck lines could be divided into 13 gene groups and three novel gene groups existed.Moreover, 14 key variable residues corresponding to gene groups division were exhibited on the homology modelling constructed based on the resolved protein structure of DuMHC I. This study explicit the characteristics of DuMHC I in the two duck lines and could contribute to design effective diagnostics and vaccines for the species against various infections.

Indexed as

Polymorphism, GeneticAllelesAmino Acid SequenceAnimalsCloning, MolecularDNA, ComplementaryDucksGenes, MHC Class IInfectionsPhylogenyDNA, Complementary

Identifiers

PMID28674238
OpenAlexW2624712183

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.