ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2017
Effects of Chronic Social Defeat Stress on Sleep and Circadian Rhythms Are Mitigated by Kappa-Opioid Receptor Antagonism.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
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Who cites it
68 citing papers in PubMed, 112 citations in OpenAlex.
- Stress-induced adaptations in nucleus accumbens dopamine D1 receptor-expressing cells correspond to social avoidance behavior in male mice.IBRO neuroscience reports · 2026Article
- The Role of Kappa-Opioid Receptor/Dynorphin System in Modulating Neural-Circuits of Depression and Anxiety-A Review.Journal of cellular and molecular medicine · 2026Review
- Kappa opioid receptor antagonism in neuropsychiatry: from molecular mechanisms to clinical prospects.European archives of psychiatry and clinical neuroscience · 2026Review
- Effects of adjunctive brexpiprazole with selective serotonin reuptake inhibitor treatment on anxiety and sleep architecture in mice.The international journal of neuropsychopharmacology · 2026Article
- Sleep patterns predicting stress resilience are dependent on sex.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Correspondence between sleep patterns and anhedonia in adult male mice exposed to early-life stress.Translational psychiatry · 2025Article
- Inflammatory pain in mice induces light cycle-dependent effects on sleep architecture.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2025Article
- Disrupted circadian rhythms and opioid-mediated adverse effects: Bidirectional relationship and putative mechanisms.Journal of neuroendocrinology · 2025Review
- Role of the amygdala opioid system in the effects of stress on the post-learning sleep patterns of male Wistar rats.Iranian journal of basic medical sciences · 2025Article
- Acute sleep disruption reduces fear memories in male and female mice.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024Article
- Resilience to Chronic Stress Is Characterized by Circadian Brain-Liver Coordination.Biological psychiatry global open science · 2024Article
- Psychometric evaluation of the Chinese version of the hospital-acquired insomnia scale (HAIS) and analysis of influencing factors.BMC psychiatry · 2024Article
- Acute sleep deprivation reduces fear memories in male and female mice.bioRxiv : the preprint server for biology · 2024Article
- Differential effects of the stress peptides PACAP and CRF on sleep architecture in mice.NPP - digital psychiatry and neuroscience · 2024Article
- Does sleep promote adaptation to acute stress: An experimental study.Neurobiology of stress · 2024Article
- Translational models of stress and resilience: An applied neuroscience methodology review.Neuroscience applied · 2024Review
- Early life stress in male mice blunts responsiveness in a translationally-relevant reward task.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2023Article
- Social Psychopharmacology: Novel Approaches to Treat Deficits in Social Motivation in Schizophrenia.Schizophrenia bulletin · 2023Review
- Bright light treatment counteracts stress-induced sleep alterations in mice, via a visual circuit related to the rostromedial tegmental nucleus.PLoS biology · 2023Article
- Stress-Induced Changes in the Endogenous Opioid System Cause Dysfunction of Pain and Emotion Regulation.International journal of molecular sciences · 2023Review
8 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
Abstract
Stress plays a critical role in the neurobiology of mood and anxiety disorders. Sleep and circadian rhythms are affected in many of these conditions. Here we examined the effects of chronic social defeat stress (CSDS), an ethological form of stress, on sleep and circadian rhythms. We exposed male mice implanted with wireless telemetry transmitters to a 10 day CSDS regimen known to produce anhedonia (a depressive-like effect) and social avoidance (an anxiety-like effect). EEG, EMG, body temperature, and locomotor activity data were collected continuously during the CSDS regimen and a 5 day recovery period. CSDS affected numerous endpoints, including paradoxical sleep (PS) and slow-wave sleep (SWS), as well as the circadian rhythmicity of body temperature and locomotor activity. The magnitude of the effects increased with repeated stress, and some changes (PS bouts, SWS time, body temperature, locomotor activity) persisted after the CSDS regimen had ended. CSDS also altered mRNA levels of the circadian rhythm-related gene
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.