Evidence map›Paper›PMID 28674145›Full record

ArticleBMJ open2017

The STRATAA study protocol: a programme to assess the burden of enteric fever in Bangladesh, Malawi and Nepal using prospective population census, passive surveillance, serological studies and healthcare utilisation surveys.

Thomas C Darton, James E Meiring, Susan Tonks, Md Arifuzzaman Khan, Farhana Khanam, Mila Shakya, Deus Thindwa, Stephen Baker, Buddha Basnyat, John D Clemens and 11 more

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 1 pooled it
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 1 synthesis or guideline pooled it, 77 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
  6. TheVaccines · 2025
    Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. The Enterics for Global Health (EFGH)Open forum infectious diseases · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
  18. Observational
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

21 authors at 8 institutions in 8 countries.

Thomas C DartonThe Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
James E MeiringDepartment of Paediatrics, Oxford Vaccine Group,University of Oxford, and the NIHR Oxford Biomedical Research Centre, Oxford, UK.ORCID 0000-0001-9183-5174
Susan TonksDepartment of Paediatrics, Oxford Vaccine Group,University of Oxford, and the NIHR Oxford Biomedical Research Centre, Oxford, UK.
Md Arifuzzaman KhanInternational Centre for Diarrhoeal Diseases Research, Dhaka, Bangladesh.
Farhana KhanamInternational Centre for Diarrhoeal Diseases Research, Dhaka, Bangladesh.
Mila ShakyaOxford University Clinical Research Unit, Patan Academy of Health Sciences, Kathmandu, Nepal.
Deus ThindwaMalawi Liverpool Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Stephen BakerThe Hospital for Tropical Diseases, Wellcome Trust Major Overseas Programme, Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam.
Buddha BasnyatOxford University Clinical Research Unit, Patan Academy of Health Sciences, Kathmandu, Nepal.
John D ClemensInternational Centre for Diarrhoeal Diseases Research, Dhaka, Bangladesh.
Gordon DouganThe Wellcome Trust Sanger Institute, Cambridgeshire, UK.
Christiane DolecekNuffield Department of Medicine, Centre for Tropical Medicine and Global Health, University of Oxford, Oxford, UK.
Sarah J DunstanThe Peter Doherty Institute for Infection and Immunity,The University of Melbourne, Melbourne, Australia.
Melita A GordonMalawi Liverpool Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Robert S HeydermanMalawi Liverpool Wellcome Trust Clinical Research Programme, University of Malawi College of Medicine, Blantyre, Malawi.
Kathryn E HoltCentre for Systems Genomics,University of Melbourne, Victoria, Australia.
Virginia E PitzerDepartment of Epidemiology of Microbial Diseases, Yale School of Public Health, Yale University, New Haven, Connecticut, USA.
Firdausi QadriInternational Centre for Diarrhoeal Diseases Research, Dhaka, Bangladesh.
K ZamanInternational Centre for Diarrhoeal Diseases Research, Dhaka, Bangladesh.
Andrew J PollardDepartment of Paediatrics, Oxford Vaccine Group,University of Oxford, and the NIHR Oxford Biomedical Research Centre, Oxford, UK.
STRATAA Study Consortium
International Centre for Diarrhoeal Disease Research · BDUniversity of Oxford · GBUniversity of Liverpool · GBPatan Academy of Health Sciences · NPThe University of Melbourne · AUWellcome Sanger Institute · GBMahidol University · THYale University · US

Funding

Wellcome TrustWellcome Trust 106158/Z/14/Z
6 · The paper itself

Abstract

introductionInvasive infections caused by METHODS/

designUsing census-defined denominator populations of ≥100 000 individuals at sites in Malawi, Bangladesh and Nepal, the primary outcome is to characterise the burden of enteric fever in these populations over a 24-month period. During passive surveillance, clinical and household data, and laboratory samples will be collected from febrile individuals. In parallel, healthcare utilisation and water, sanitation and hygiene surveys will be performed to characterise healthcare-seeking behaviour and assess potential routes of transmission. The rates of both undiagnosed and subclinical exposure to typhoidal ETHICS AND DISSEMINATION: This protocol has been ethically approved by the Oxford Tropical Research Ethics Committee, the icddr,b Institutional Review Board, the Malawian National Health Sciences Research Committee and College of Medicine Research Ethics Committee and Nepal Health Research Council. The study is being conducted in accordance with the principles of the Declaration of Helsinki and Good Clinical Practice. Informed consent was obtained before study enrolment. Results will be submitted to international peer-reviewed journals and presented at international conferences. TRIAL REGISTRATION NUMBER: ISRCTN 12131979. ETHICS REFERENCES: Oxford (Oxford Tropical Research Ethics Committee 39-15).Bangladesh (icddr,b Institutional Review Board PR-15119).Malawi (National Health Sciences Research Committee 15/5/1599).Nepal (Nepal Health Research Council 306/2015).

Indexed as

CensusesAdolescentBangladeshCarrier StateChildChild, PreschoolCost of IllnessFemaleHealth ResourcesHumansIncidenceInfantInfant, NewbornMalawiMaleModels, Theoreticalafricaasiadiagnosisenteric feverfebrile illnesshealthcare utilisationinfection transmissionresource-limited settingsalmonella paratyphi asalmonella typhiseroepidemiologyserosurveillancevaccination programme

Identifiers

PMID28674145
PMCPMC5726077
OpenAlexW2732320847

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.