Evidence map›Paper›PMID 28674072›Full record

ArticleJournal of bacteriology2017

Counterbalancing Regulation in Response Memory of a Positively Autoregulated Two-Component System.

Rong Gao, Katherine A Godfrey, Mahir A Sufian, Ann M Stock

Abstract read
In one paragraph

Article in Journal of bacteriology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Control of theEcoSal Plus · 2019
    Review
  4. Article
  5. Article
  6. Learning from Adversity?Journal of bacteriology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rong GaoCenter for Advanced Biotechnology and Medicine, Department of Biochemistry and Molecular Biology, Rutgers University-Robert Wood Johnson Medical School, Piscataway, New Jersey, USA.
Katherine A GodfreyCenter for Advanced Biotechnology and Medicine, Department of Biochemistry and Molecular Biology, Rutgers University-Robert Wood Johnson Medical School, Piscataway, New Jersey, USA.
Mahir A SufianCenter for Advanced Biotechnology and Medicine, Department of Biochemistry and Molecular Biology, Rutgers University-Robert Wood Johnson Medical School, Piscataway, New Jersey, USA.
Ann M StockCenter for Advanced Biotechnology and Medicine, Department of Biochemistry and Molecular Biology, Rutgers University-Robert Wood Johnson Medical School, Piscataway, New Jersey, USA stock@cabm.rutgers.edu.ORCID http://orcid.org/0000-0002-0446-8079

Funding

STRUCTURE/FUNCTION OF RESPONSE REGULATOR PROTEINSR01GM047958 · NIGMS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI STOCK, ANN M. · 1992 to 2017
$2.3M
NIGMS NIH HHS R01 GM047958
6 · The paper itself

Abstract

Fluctuations in nutrient availability often result in recurrent exposures to the same stimulus conditions. The ability to memorize the past event and use the "memory" to make adjustments to current behaviors can lead to a more efficient adaptation to the recurring stimulus. A short-term phenotypic memory can be conferred via carryover of the response proteins to facilitate the recurrent response, but the additional accumulation of response proteins can lead to a deviation from response homeostasis. We used the

Indexed as

Gene Expression Regulation, BacterialSignal TransductionBacterial ProteinsEscherichia coliEscherichia coli ProteinsModels, TheoreticalPhosphatesStress, PhysiologicalTranscription FactorsBacterial ProteinsEscherichia coli ProteinsPhoB protein, E coliPhoR protein, BacteriaPhosphatesTranscription Factorsautoregulationcomputer modelinghomeostasismemoryPhoBRsigma factorsstress responsetranscriptional regulationtranscriptional repressiontwo-component regulatory systems

Identifiers

PMID28674072
PMCPMC5573069

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.