Evidence map›Paper›PMID 28674037›Full record

ArticleHypertension (Dallas, Tex. : 1979)2017

Blood Pressure and Risk of Cardiovascular Events in Patients on Chronic Hemodialysis: The CRIC Study (Chronic Renal Insufficiency Cohort).

Nisha Bansal, Charles E McCulloch, Feng Lin, Arnold Alper, Amanda H Anderson, Magda Cuevas, Alan S Go, Radhakrishna Kallem, John W Kusek, Claudia M Lora and 9 more

Abstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Guideline
  2. Guideline
  3. The Japanese Society of Hypertension Guidelines for the Management of Hypertension (JSH 2019).Hypertension research : official journal of the Japanese Society of Hypertension · 2019
    Guideline
  4. Guideline
  5. Trial
  6. Treating Home Versus Predialysis Blood Pressure Among In-Center Hemodialysis Patients: A Pilot Randomized Trial.American journal of kidney diseases : the official journal of the National Kidney Foundation · 2021
    Trial
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Pre-dialysis blood pressure and cardiovascular mortality in Japan: need for much stricter control?Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Nisha BansalFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.). nbansal@nephrology.washington.edu.
Charles E McCullochFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
Feng LinFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
Arnold AlperFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
Amanda H AndersonFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
Magda CuevasFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
Alan S GoFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
Radhakrishna KallemFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
John W KusekFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
Claudia M LoraFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
Eva LustigovaFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
Akinlolu OjoFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
Mahboob RahmanFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
Cassianne Robinson-CohenFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
Raymond R TownsendFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
Jackson WrightFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
Dawei XieFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
Chi-Yuan HsuFrom the Division of Nephrology, University of Washington (N.B., C.R.-C.); Department of Biostatistics and Epidemiology (C.E.M., F.L.), Division of Nephrology (C.-y.H), University of California, San Francisco; Division of Nephrology, Tulane University (A.A., E.L.); Department of Epidemiology and Biostatistics (A.H.A., M.C., D.X.), Division of Nephrology (R.K., R.R.T.), Perelman School of Medicine, University of Pennsylvania; Kaiser Permanente Northern California Division of Research (A.S.G., C.-y.H.); National Institute of Diabetes and Digestive and Kidney Diseases (J.W.K.); Division of Nephrology, University of Chicago, Illinois (C.M.L.); Division of Nephrology, University of Arizona (A.O.); and Division of Nephrology (M.R.), Division of Cardiology (J.W.), Case Western Reserve University (M.R., J.W.).
CRIC Study Investigators*

Funding

UCSF CLINICAL AND TRANSLATIONAL SCIENCE INSTITUTEUL1RR024131 · NCRR · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI JOHNSTON, S. CLAIBORNE · 2006 to 2011
$111.2M
Michigan Institute for Clinical and Health Research (MICHR)UL1TR002240 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI LUMENG, JULIE C, MASHOUR, GEORGE ALEXANDER · 2017 to 2022
$54.9M
Scientific and Data Coordinating Center(SDCC) for the P*U01DK060990 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI FELDMAN, HAROLD I · 2001 to 2017
$50.1M
Clinical and Translational Science Collaborative of ClevelandUL1TR000439 · NCATS · CASE WESTERN RESERVE UNIVERSITY · PI KONSTAN, MICHAEL W. · 2012 to 2016
$50.0M
Michigan Institute for Clinical and Health Research (MCHR)UL1TR000433 · NCATS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI MASHOUR, GEORGE ALEXANDER · 2012 to 2016
$49.9M
Institutional Clinical and Translational Science AwardUL1TR000003 · NCATS · UNIVERSITY OF PENNSYLVANIA · PI FITZGERALD, GARRET A · 2012 to 2015
$38.9M
Tulane COBRE in Cardiometabolic Diseases Clinical Research CoreP20GM109036 · NIGMS · TULANE UNIVERSITY OF LOUISIANA · PI Ning Liu · 2016 to 2026
$25.3M
Zonulin Antibodies in Intestinal Permeabilitiy in IDDMM01RR016500 · NCRR · UNIVERSITY OF MARYLAND BALTIMORE · PI ONUKWUGHA, EBERECHUKWU · 2002 to 2009
$20.2M
Study of the Care and Outcomes of REnal InsufficiencyU01DK060902 · NIDDK · KAISER FOUNDATION RESEARCH INSTITUTE · PI GO, ALAN S · 2001 to 2025
$19.5M
Limited Competition for the Continuation of the Chronic Renal Insufficiency CohorU01DK061021 · NIDDK · CASE WESTERN RESERVE UNIVERSITY · PI RAHMAN, MAHBOOB · 2001 to 2025
$17.3M
Prospective Renal Insufficiency Cohort Evaluation:PRICEU01DK060984 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI COHEN, DEBBIE L · 2001 to 2025
$17.0M
Prospective Cohort Study of Chronic Renal InsufficiencyU01DK061028 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI RAO, PANDURANGA S · 2001 to 2025
$16.9M
NCATS NIH HHS UL1 TR000003NCATS NIH HHS UL1 TR000424NCATS NIH HHS UL1 TR000433NCATS NIH HHS UL1 TR000439NCATS NIH HHS UL1 TR002240NCRR NIH HHS M01 RR016500NCRR NIH HHS UL1 RR024131NCRR NIH HHS UL1 RR029879NIDDK NIH HHS K01 DK092353NIDDK NIH HHS K23 DK088865NIDDK NIH HHS K24 DK092291NIDDK NIH HHS R01 DK070939NIDDK NIH HHS U01 DK060902NIDDK NIH HHS U01 DK060963NIDDK NIH HHS U01 DK060980NIDDK NIH HHS U01 DK060984NIDDK NIH HHS U01 DK060990NIDDK NIH HHS U01 DK061021NIDDK NIH HHS U01 DK061022NIDDK NIH HHS U01 DK061028NIGMS NIH HHS P20 GM109036
6 · The paper itself

Abstract

We recently reported a linear association between higher systolic blood pressure (SBP) and risk of mortality in hemodialysis patients when SBP is measured outside of the dialysis unit (out-of-dialysis-unit-SBP), despite there being a U-shaped association between SBP measured at the dialysis unit (dialysis-unit-SBP) with risk of mortality. Here, we explored the relationship between SBP with cardiovascular events, which has important treatment implications but has not been well elucidated. Among 383 hemodialysis participants enrolled in the prospective CRIC study (Chronic Renal Insufficiency Cohort), multivariable splines and Cox models were used to study the association between SBP and adjudicated cardiovascular events (heart failure, myocardial infarction, ischemic stroke, and peripheral artery disease), controlling for differences in demographics, cardiovascular disease risk factors, and dialysis parameters. Dialysis-unit-SBP and out-of-dialysis-unit-SBP were modestly correlated (

Indexed as

HypertensionKidney Failure, ChronicMyocardial InfarctionRenal DialysisStrokeAgedBlood Pressure DeterminationCohort StudiesFemaleHumansMaleMiddle AgedPrognosisProportional Hazards ModelsProspective StudiesRisk Assessmentblood pressuredialysisheart failurerenal dialysisstroke

Identifiers

PMID28674037
PMCPMC5521215

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.