Evidence map›Paper›PMID 28674028›Full record

SynthesisBlood2017

Gemtuzumab ozogamicin in infants with AML: results from the Children's Oncology Group trials AAML03P1 and AAML0531.

Erin M Guest, Richard Aplenc, Lillian Sung, Susana C Raimondi, Betsy A Hirsch, Todd A Alonzo, Robert B Gerbing, Yi-Cheng Jim Wang, Samir B Kahwash, Amy Heerema-McKenney and 2 more

Open access · bronzeAbstract readLetterMeta-Analysis
In one paragraph

Synthesis in Blood, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Guideline
  2. Gemtuzumab Ozogamicin Improves Event-Free Survival and Reduces Relapse in PediatricJournal of clinical oncology : official journal of the American Society of Clinical Oncology · 2021
    Trial
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Acute Leukemia in Infants.Current oncology reports · 2021
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 10 institutions in 2 countries.

Erin M GuestChildren's Mercy Kansas City, Kansas City, MO.ORCID 0000-0003-2482-5608
Richard AplencChildren's Hospital of Philadelphia, Philadelphia, PA.
Lillian SungThe Hospital for Sick Children, Toronto, ON, Canada.
Susana C RaimondiSt. Jude Children's Research Hospital, Memphis, TN.
Betsy A HirschDepartment of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN.
Todd A AlonzoDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA.
Robert B GerbingChildren's Oncology Group, Monrovia, CA.
Yi-Cheng Jim WangChildren's Oncology Group, Monrovia, CA.
Samir B KahwashNationwide Children's Hospital, Columbus, OH.
Amy Heerema-McKenneyCleveland Clinic Foundation, Cleveland, OH; and.
Soheil MeshinchiFred Hutchinson Cancer Center, Seattle, WA.
Alan S GamisChildren's Mercy Kansas City, Kansas City, MO.
Children's Mercy Hospital · USChildren's Oncology Group · USChildren's Hospital of Philadelphia · USCleveland Clinic · USFred Hutch Cancer Center · USHospital for Sick Children · CANationwide Children's Hospital · USSt. Jude Children's Research Hospital · USUniversity of Minnesota · USUniversity of Southern California · US

Funding

NCTN BIQSFP ANBL1531 (NRT)U10CA180886 · NCI · PUBLIC HEALTH INSTITUTE · PI Douglas S. Hawkins · 2014 to 2026
$390.6M
COG FOREIGN ACCRUALU10CA098543 · NCI · NATIONAL CHILDHOOD CANCER FOUNDATION · PI ADAMSON, PETER C. · 2003 to 2013
$335.5M
COG SDMC - Statistics CoreU10CA180899 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TODD A ALONZO · 2014 to 2026
$132.8M
Biology/prognostic implications of Flt3 mutations in AMLR01CA114563 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI MESHINCHI, SOHEIL · 2005 to 2016
$4.4M
NCI NIH HHS R01 CA114563NCI NIH HHS U10 CA098543NCI NIH HHS U10 CA180886NCI NIH HHS U10 CA180899
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AminoglycosidesAntibodies, Monoclonal, HumanizedAntineoplastic Agents, ImmunologicalAntineoplastic Combined Chemotherapy ProtocolsClinical Trials, Phase III as TopicFemaleFollow-Up StudiesGemtuzumabHepatic Veno-Occlusive DiseaseHumansInfantKaplan-Meier EstimateMaleMulticenter Studies as TopicPilot ProjectsProportional Hazards ModelsAminoglycosidesAntibodies, Monoclonal, HumanizedAntineoplastic Agents, ImmunologicalGemtuzumab

Identifiers

PMID28674028
PMCPMC5561899
OpenAlexW2724638186

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.