ArticleProceedings of the National Academy of Sciences of the United States of America2017
Disruption of a horizontally transferred phytoene desaturase abolishes carotenoid accumulation and diapause in
Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 122 citations in OpenAlex.
- Interfering with DNA repair pathways to enhance CRISPR-Cas9-mediated homology-directed repair in a chelicerate genetic model.iScience · 2026Article
- A genome sequence and efficient CRISPR/Cas9 gene editing tools for the solanaceous specialist pest Tetranychus evansi.Insect biochemistry and molecular biology · 2026Article
- Horizontally Transferred Carotenoid Genes Associated with Light-Driven ATP Synthesis to Promote Cold Adaptation in Pea Aphid,Insects · 2025Article
- Population genomics reveal multiple independent origins of pesticide resistance in the polyphagous pest, Tetranychus urticae.Communications biology · 2025Article
- Molecular basis governing diapause and pigmentation in the hawthorn spider mite, Amphitetranychus viennensis.BMC biology · 2025Article
- SYNCAS based CRISPR-Cas9 gene editing in predatory mites, whiteflies and stinkbugs.Insect biochemistry and molecular biology · 2025Article
- Chromosome-level genome assembly of the two-spotted spider mite Tetranychus urticae.Scientific data · 2024Article
- Uridine Diphosphate Glycosyltransferases (UGTs) Involved in the Carotenoid-Based Body Color Difference betweenInsects · 2023Article
- Astaxanthin: Past, Present, and Future.Marine drugs · 2023Review
- A nuclear receptor HR96-related gene underlies large trans-driven differences in detoxification gene expression in a generalist herbivore.Nature communications · 2023Article
- Intraspecific diversity in the mechanisms underlying abamectin resistance in a cosmopolitan pest.Evolutionary applications · 2023Article
- Horizontal Gene Transfer and Fusion Spread Carotenogenesis Among Diverse Heterotrophic Protists.Genome biology and evolution · 2023Article
- Biology of Two-Spotted Spider Mite (International journal of molecular sciences · 2023Article
- Carotenoids: Distribution, Function in Nature, and Analysis Using LC-Photodiode Array Detector (DAD)-MS and MS/MS System.Mass spectrometry (Tokyo, Japan) · 2023Article
- Article
- Trans-driven variation in expression is common among detoxification genes in the extreme generalist herbivore Tetranychus urticae.PLoS genetics · 2022Article
- Intradiol ring cleavage dioxygenases from herbivorous spider mites as a new detoxification enzyme family in animals.BMC biology · 2022Article
- Predicting the genomic resolution of bulk segregant analysis.G3 (Bethesda, Md.) · 2022Article
- Carotenoid modifying enzymes in metazoans.Methods in enzymology · 2022Article
- Circadian and Neuroendocrine Basis of Photoperiodism Controlling Diapause in Insects and Mites: A Review.Frontiers in physiology · 2022Review
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Authors and funding
11 authors at 6 institutions in 7 countries.
Funding
Abstract
Carotenoids underlie many of the vibrant yellow, orange, and red colors in animals, and are involved in processes ranging from vision to protection from stresses. Most animals acquire carotenoids from their diets because de novo synthesis of carotenoids is primarily limited to plants and some bacteria and fungi. Recently, sequencing projects in aphids and adelgids, spider mites, and gall midges identified genes with homology to fungal sequences encoding de novo carotenoid biosynthetic proteins like phytoene desaturase. The finding of horizontal gene transfers of carotenoid biosynthetic genes to three arthropod lineages was unprecedented; however, the relevance of the transfers for the arthropods that acquired them has remained largely speculative, which is especially true for spider mites that feed on plant cell contents, a known source of carotenoids. Pigmentation in spider mites results solely from carotenoids. Using a combination of genetic approaches, we show that mutations in a single horizontally transferred phytoene desaturase result in complete albinism in the two-spotted spider mite,
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.