Evidence map›Paper›PMID 28674000›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2017

Genome-wide screen for genes involved in eDNA release during biofilm formation by

Alicia S DeFrancesco, Nadezda Masloboeva, Adnan K Syed, Aaron DeLoughery, Niels Bradshaw, Gene-Wei Li, Michael S Gilmore, Suzanne Walker, Richard Losick

Open access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 78 papers.

0numbers the graph read from it
0cells of the map it votes in
78citing papers in PubMed
4.0field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

78 citing papers in PubMed, 111 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. SpbR controls lipoteichoic acid length by directly inhibiting signal peptidase SpsB inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Antifungal Activity of 5-Fluorouridine AgainstMolecules (Basel, Switzerland) · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Biofilm formation byProceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  12. Article
  13. Article
  14. SCCBiofilm · 2024
    Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Beyond the double helix: the multifaceted landscape of extracellular DNA inFrontiers in cellular and infection microbiology · 2024
    Review
  20. Article

18 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Alicia S DeFrancescoDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138.
Nadezda MasloboevaDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138.
Adnan K SyedDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138.
Aaron DeLougheryDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138.
Niels BradshawDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138.
Gene-Wei LiDepartment of Biology, Massachusetts Institute of Technology, Cambridge, MA 02142.
Michael S GilmoreDepartment of Ophthalmology, Harvard Medical School, Massachusetts Eye and Ear Infirmary, Boston, MA 02114.
Suzanne WalkerDepartment of Microbiology and Immunobiology, Harvard Medical School, Boston, MA 02115.
Richard LosickDepartment of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138; losick@mcb.harvard.edu.
Harvard University · USMassachusetts Institute of Technology · US

Funding

Technical Mother Machine CoreP01AI083214 · NIAID · SCHEPENS EYE RESEARCH INSTITUTE · PI Michael S Gilmore · 2009 to 2026
$39.4M
Role of RNA Polymerase in Bacterial DifferentionR01GM018568 · NIGMS · HARVARD UNIVERSITY · PI LOSICK, RICHARD MARC · 1985 to 2018
$11.5M
ROLE OF RNA POLYMERASE IN BACTERIAL DIFFERENTIATIONR37GM018568 · NIGMS · HARVARD UNIVERSITY · PI LOSICK, RICHARD MARC · 1990 to 1999
–
NIAID NIH HHS P01 AI083214NIGMS NIH HHS R01 GM018568NIGMS NIH HHS R37 GM018568
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

BiofilmsGenes, BacterialCell WallCongo RedDNA, BacterialDNA Transposable ElementsDrug Resistance, BacterialGene Expression Regulation, BacterialGenome, BacterialGenomicsMutationStaphylococcus aureusVirulenceCongo RedDNA, BacterialDNA Transposable Elementsbiofilmcyclic-di-AMPeDNAStaphylococcus aureus

Identifiers

PMID28674000
PMCPMC5530685
OpenAlexW2729754411

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.