ArticleInternational journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2017
Respiratory viruses detected in Mexican children younger than 5 years old with community-acquired pneumonia: a national multicenter study.
Article in International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.
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Who cites it
41 citing papers in PubMed, 1 synthesis or guideline pooled it, 70 citations in OpenAlex.
- Childcare centre attendance and health, growth, and development among children aged 0-3 years in low- and middle-income countries: A systematic review.Journal of global health · 2024Pooled it
- Associated factors of microorganisms causing lower respiratory tract infections in children hospitalized between 2019 and 2022 in a private hospital in Lima, PerúBiomedica : revista del Instituto Nacional de Salud · 2026Article
- The prevalence and role of human respiratory syncytial virus in pediatric respiratory tract infections: a systematic review and meta-analysis of global data.EClinicalMedicine · 2026Article
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- Wastewater-Based Surveillance of Respiratory Viruses in the SARS-CoV-2 Post-Pandemic Period in Mexico.Viruses · 2026Article
- Respiratory virus dynamics in a tropical region: Insights from Yucatán, México (2018-2024).Epidemiology and infection · 2026Article
- National respiratory syncytial virus acute respiratory infection burden of disease estimate in Mexican children under 2 years.Frontiers in pediatrics · 2026Article
- Position statement of the Mexican Association of Pediatrics on the immunoprevention of respiratory syncytial virus infection during pregnancy and infancy.World journal of pediatrics : WJP · 2026Review
- Impact of COVID-19 on the epidemiological features of mycoplasma pneumoniae infection in children with community-acquired pneumonia in Ganzhou, China.Frontiers in immunology · 2026Article
- Genotypic Diversity of Human Rhinovirus in Children with Pneumonia Before and During the COVID-19 Pandemic in Mexico.Pathogens (Basel, Switzerland) · 2025Article
- Respiratory Infant Mortality Rate by Month of Birth in Mexico.Epidemiologia (Basel, Switzerland) · 2025Article
- Cross-reactivity IgG, viral load, severity and vaccination outcome as an approach for understanding humoral immune response against SARS-CoV-2.BMC infectious diseases · 2025Article
- Epidemiological and Clinical Changes in RSV-Associated Pneumonia in Children in Mexico Before and During the COVID 19 Pandemic.Infectious disease reports · 2025Article
- Clinical Characteristics of Adenovirus Pneumonia in Children.Pathogens (Basel, Switzerland) · 2025Article
- Titers of IgG, IgM, and IgA Against SARS-CoV-2 in Healthcare Workers from a General Hospital in Mexico City.Diseases (Basel, Switzerland) · 2025Article
- Epidemiological and clinical profile of viral respiratory infections in children under 5 years at pre- and post-COVID-19 era in Praia, Cabo Verde.Tropical medicine & international health : TM & IH · 2025Article
- Genotypic Characterization of Human Respiratory Syncytial Viruses Detected in Mexico Between 2021 and 2024.Viruses · 2025Article
- Article
- RSV Infection in Refugees and Asylum Seekers: A Systematic Review and Meta-Analysis.Epidemiologia (Basel, Switzerland) · 2024Review
- Increased Incidence of Rhinovirus Pneumonia in Children During the COVID-19 Pandemic in Mexico.Advances in virology · 2024Article
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Authors and funding
21 authors at 11 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAcute respiratory infections are the leading cause of mortality in children worldwide, especially in developing countries. Pneumonia accounts for 16% of all deaths of children under 5 years of age and was the cause of death of 935000 children in 2015. Despite its frequency and severity, information regarding its etiology is limited. The aim of this study was to identify respiratory viruses associated with community-acquired pneumonia (CAP) in children younger than 5 years old.
methodsOne thousand four hundred and four children younger than 5 years of age with a clinical and/or radiological diagnosis of CAP in 11 hospitals in Mexico were included. Nasal washes were collected, placed in viral medium, and frozen at -70°C until processing. The first 832 samples were processed using the multiplex Bio-Plex/Luminex system and the remaining 572 samples using the Anyplex multiplex RT-PCR. Clinical data regarding diagnosis, clinical signs and symptoms, radiographic pattern, and risk factors were obtained and recorded.
resultsOf the samples tested, 81.6% were positive for viruses. Respiratory syncytial virus (types A and B) was found in 23.7%, human enterovirus/rhinovirus in 16.6%, metapneumovirus in 5.7%, parainfluenza virus (types 1-4) in 5.5%, influenza virus (types A and B) in 3.6%, adenovirus in 2.2%, coronavirus (NL63, OC43, 229E, and HKU1) in 2.2%, and bocavirus in 0.4%. Co-infection with two or more viruses was present in 22.1%; 18.4% of the samples were negative. Using biomass for cooking, daycare attendance, absence of breastfeeding, and co-infections were found to be statistically significant risk factors for the presence of severe pneumonia.
conclusionsRespiratory syncytial virus (types A and B), human enterovirus/rhinovirus, and metapneumovirus were the respiratory viruses identified most frequently in children younger than 5 years old with CAP. Co-infection was present in an important proportion of the children.
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