ArticleJournal of translational medicine2017
The clinical importance of tumour-infiltrating macrophages and dendritic cells in periampullary adenocarcinoma differs by morphological subtype.
Article in Journal of translational medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed, 40 citations in OpenAlex.
- Impact of body composition on prognostic stratification and survival in periampullary carcinoma after pancreatoduodenectomy.Abdominal radiology (New York) · 2026Article
- Beneficial Probiotics with New Cancer Therapies for Improved Treatment of Hepatocellular Carcinoma.Diseases (Basel, Switzerland) · 2025Review
- Extracellular vesicles at the crossroad between cancer progression and immunotherapy: focus on dendritic cells.Journal of translational medicine · 2024Review
- The application of MARCO for immune regulation and treatment.Molecular biology reports · 2024Review
- Article
- Targeting myeloid suppressive cells revives cytotoxic anti-tumor responses in pancreatic cancer.iScience · 2022Article
- Adjuvant therapy for periampullary carcinoma and the significance of histopathological typing: A systematic review.Translational oncology · 2022Review
- High Infiltration of CD68+/CD163- Macrophages Is an Adverse Prognostic Factor after Neoadjuvant Chemotherapy in Esophageal and Gastric Adenocarcinoma.Journal of innate immunity · 2022Article
- Infiltration of CD1a-positive dendritic cells in advanced laryngeal cancer correlates with unfavorable outcomes post-laryngectomy.BMC cancer · 2021Article
- Upregulated CD58 is associated with clinicopathological characteristics and poor prognosis of patients with pancreatic ductal adenocarcinoma.Cancer cell international · 2021Article
- Single-cell characterization of macrophages in glioblastoma reveals MARCO as a mesenchymal pro-tumor marker.Genome medicine · 2021Article
- Nanocarrier-Based Drug Delivery for Melanoma Therapeutics.International journal of molecular sciences · 2021Review
- The Scavenger Receptor MARCO Expressed by Tumor-Associated Macrophages Are Highly Associated With Poor Pancreatic Cancer Prognosis.Frontiers in oncology · 2021Article
- Tumor circulome in the liquid biopsies for cancer diagnosis and prognosis.Theranostics · 2020Review
- Topographical Distribution and Spatial Interactions of Innate and Semi-Innate Immune Cells in Pancreatic and Other Periampullary Adenocarcinoma.Frontiers in immunology · 2020Article
- Tumor-Associated CD68Frontiers in oncology · 2020Article
- Complement inhibitor factor H expressed by breast cancer cells differentiates CD14Oncoimmunology · 2020Article
- Human Tumor-Infiltrating Dendritic Cells: From in Situ Visualization to High-Dimensional Analyses.Cancers · 2019Review
- Relationship between mismatch repair immunophenotype and long-term survival in patients with resected periampullary adenocarcinoma.Journal of translational medicine · 2018Article
- Tumor-associated macrophage-derived cytokines enhance cancer stem-like characteristics through epithelial-mesenchymal transition.OncoTargets and therapy · 2018Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundDendritic cells (DC) and tumour-associated macrophages (TAM) are essential in linking the innate and adaptive immune response against tumour cells and tumour progression. These cells are also potential target for immunotherapy as well as providing a handle to investigate immune status in the tumour microenvironment. The aim of the present study was to examine their impact on prognosis and chemotherapy response in periampullary adenocarcinoma, including pancreatic cancer, with particular reference to morphological subtype.
methodsThe density of tolerogenic immature CD1a
resultsHigh density of CD1a
conclusionsThe results from this study demonstrate that high infiltration of tolerogenic immature DCs independently predicts a shorter survival in patients with PB-type periampullary adenocarcinoma, and that high density of the MARCO
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