Evidence map›Paper›PMID 28673258›Full record

ArticleBMC genomics2017

Differential regulation of miRNA and mRNA expression in the myocardium of Nrf2 knockout mice.

Justin M Quiles, Madhusudhanan Narasimhan, Gobinath Shanmugam, Brett Milash, John R Hoidal, Namakkal S Rajasekaran

Open access · goldAbstract read
In one paragraph

Article in BMC genomics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
  2. Article
  3. Diagnostic and treatment value ofJournal of thoracic disease · 2023
    Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. DNA damage-free iPS cells exhibit potential to yield competent cardiomyocytes.American journal of physiology. Heart and circulatory physiology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Justin M QuilesCardiac Aging & Redox Signaling Laboratory, Division of Molecular & Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, BMR2 Room 533|901 19th Street South, Birmingham, AL, 35294-2180, USA.
Madhusudhanan NarasimhanDepartment of Pharmacology and Neuroscience, Texas Tech University Health Sciences Center, Lubbock, TX, 79430, USA.
Gobinath ShanmugamCardiac Aging & Redox Signaling Laboratory, Division of Molecular & Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, BMR2 Room 533|901 19th Street South, Birmingham, AL, 35294-2180, USA.
Brett MilashHuntsman Cancer Institute, Salt Lake City, USA.
John R HoidalDivision of Pulmonary, Salt Lake City, USA.
Namakkal S RajasekaranCardiac Aging & Redox Signaling Laboratory, Division of Molecular & Cellular Pathology, Department of Pathology, University of Alabama at Birmingham, BMR2 Room 533|901 19th Street South, Birmingham, AL, 35294-2180, USA. rajnsr@uabmc.edu.
University of Alabama at Birmingham · USHuntsman Cancer Institute · USPulmonary Associates · USTexas Tech University Health Sciences Center · US

Funding

Reductive Stress Induces Proteotoxic Cardiac DiseaseR01HL118067 · NHLBI · UNIVERSITY OF UTAH · PI NAMAKKAL SOORAPPAN, RAJASEKARAN · 2013 to 2021
$4.5M
Antioxidant Defense Mechanisms: Nrf2/Keap1 Signaling in Aging HeartR03AG042860 · NIA · UNIVERSITY OF UTAH · PI NAMAKKAL SOORAPPAN, RAJASEKARAN · 2012 to 2013
$145k
NHLBI NIH HHS R01 HL118067NIA NIH HHS R03 AG042860
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsGene Expression RegulationMaleMice, Inbred C57BLMice, KnockoutMicroRNAsMitochondriaMyocardiumNF-E2-Related Factor 2Oxidation-ReductionOxidative StressRNA, MessengerTranscription, GeneticTranscriptomeMicroRNAsNfe2l2 protein, mouseNF-E2-Related Factor 2RNA, MessengerAntioxidantDifferential expressionHeartmicroRNAmRNANrf2RedoxRNA sequencing

Identifiers

PMID28673258
PMCPMC5496330
OpenAlexW2729725682

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.