Evidence map›Paper›PMID 28673234›Full record

ArticleBMC genetics2017

Genomic variability in Mexican chicken population using copy number variants.

E Gorla, M C Cozzi, S I Román-Ponce, F J Ruiz López, V E Vega-Murillo, S Cerolini, A Bagnato, M G Strillacci

Open access · diamondAbstract read
In one paragraph

Article in BMC genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
4.2field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 55 citations in OpenAlex.

  1. Article
  2. Genome-Wide Analysis of Copy Number Variation in Vietnamese Local Chickens.Animals : an open access journal from MDPI · 2026
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  13. Fourth Report on Chicken Genes and Chromosomes 2022.Cytogenetic and genome research · 2022
    Review
  14. Article
  15. Article
  16. Copy Number Variants in Four Italian Turkey Breeds.Animals : an open access journal from MDPI · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

E GorlaDepartment of Veterinary Medicine, Universitá degli Studi di Milano, Via Celoria 10, 20133, Milan, Italy.
M C CozziDepartment of Veterinary Medicine, Universitá degli Studi di Milano, Via Celoria 10, 20133, Milan, Italy.
S I Román-PonceCentro Nacional de Investigación en Fisiología y Mejoramiento Animal, Instituto Nacional de Investigaciones Forestales, Agricola y Pecuarias (INIFAP), Km.1 Carretera a Colón, Auchitlán, 76280, Querétaro, CP, Mexico.
F J Ruiz LópezCentro Nacional de Investigación en Fisiología y Mejoramiento Animal, Instituto Nacional de Investigaciones Forestales, Agricola y Pecuarias (INIFAP), Km.1 Carretera a Colón, Auchitlán, 76280, Querétaro, CP, Mexico.
V E Vega-MurilloCentro Nacional de Investigación en Fisiología y Mejoramiento Animal, Instituto Nacional de Investigaciones Forestales, Agricola y Pecuarias (INIFAP), Melchor Ocampo # 234 Desp. 313, Col. Centro Veracruz, C.P. 91700, Veracruz, Mexico.
S CeroliniDepartment of Veterinary Medicine, Universitá degli Studi di Milano, Via Celoria 10, 20133, Milan, Italy.
A BagnatoDepartment of Veterinary Medicine, Universitá degli Studi di Milano, Via Celoria 10, 20133, Milan, Italy.
M G StrillacciDepartment of Veterinary Medicine, Universitá degli Studi di Milano, Via Celoria 10, 20133, Milan, Italy. maria.strillacci@unimi.it.ORCID 0000-0002-8972-1730
University of Milan · ITInstituto Nacional de Investigaciones Forestales Agrícolas y Pecuarias · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCopy number variations are genome polymorphism that influence phenotypic variation and are an important source of genetic variation in populations. The aim of this study was to investigate genetic variability in the Mexican Creole chicken population using CNVs.

resultsThe Hidden Markov Model of the PennCNV software detected a total of 1924 CNVs in the genome of the 256 samples processed with Axiom® Genome-Wide Chicken Genotyping Array (Affymetrix). The mapped CNVs comprised 1538 gains and 386 losses, resulting at population level in 1216 CNV regions (CNVRs), of which 959 gains, 226 losses and 31 complex (i.e. containing both losses and gains). The CNVRs covered a total of 47 Mb of the whole genome sequence length, corresponding to 5.12% of the chicken galGal4 autosome assembly.

conclusionsThis study allowed a deep insight into the structural variation in the genome of unselected Mexican chicken population, which up to now has not been genetically characterized. The genomic study disclosed that the population, even if presenting extreme morphological variation, cannot be organized in differentiated genetic subpopulations. Finally this study provides a chicken CNV map based on the 600 K SNP chip array jointly with a genome-wide gene copy number estimates in a native unselected for more than 500 years chicken population.

Indexed as

DNA Copy Number VariationsPolymorphism, Single NucleotideAnimalsChickensGenetic MarkersGenomeMexicoGenetic MarkersChickenCopy number variantGenetic variability

Identifiers

PMID28673234
PMCPMC5496433
OpenAlexW2725834610

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.