ArticleExperimental and therapeutic medicine2017
Predictive values of urine paraquat concentration, dose of poison, arterial blood lactate and APACHE II score in the prognosis of patients with acute paraquat poisoning.
Article in Experimental and therapeutic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.
- Serum creatinine in predicting mortality after paraquat poisoning: A systematic review and meta-analysis.PloS one · 2023Pooled it
- Pooled it
- Predictive value of the maximum serum creatinine value and growth rate in acute paraquat poisoning patients.Scientific reports · 2018Trial
- Clinical characteristics and early admission predictors of in-hospital death in acute paraquat poisoning: a retrospective cohort study of 128 patients.Frontiers in medicine · 2026Article
- Construction of a clinical nursing pathway for acute paraquat poisoning: Evidence-based research.Heliyon · 2023Article
- Effects of early repeated hemoperfusion combined with hemodialysis on the prognosis of patients with paraquat poisoning.American journal of translational research · 2023Article
- Prognostic Value of the Average Lung CT Number in Patients with Acute Paraquat Poisoning.Emergency medicine international · 2023Article
- Risk factors and optimal predictive scoring system of mortality for children with acute paraquat poisoning.World journal of clinical cases · 2022Article
- Comparison of Biochemical Parameters between Mouse Model and Human after Paraquat Poisoning.BioMed research international · 2022Article
- A Paper-Based Analytical Device for Analysis of Paraquat in Urine and Its Validation with Optical-Based Approaches.Diagnostics (Basel, Switzerland) · 2020Article
- Serum anion gap at admission as a predictor of the survival of patients with paraquat poisoning: A retrospective analysis.Medicine · 2020Observational
- Hyperamylasemia as an early predictor of mortality in patients with acute paraquat poisoning.The Journal of international medical research · 2020Article
- Clinical Features, Treatment, Prognosis, and Mortality in Paraquat Poisonings: A Hospital-Based Study in Iran.Journal of research in pharmacy practiceArticle
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5 authors at 1 institution in 1 country.
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Abstract
The present study investigated the predictive values of urine paraquat (PQ) concentration, dose of poison, arterial blood lactate and Acute Physiology and Chronic Health Evaluation (APACHE) II score in the prognosis of patients with acute PQ poisoning. A total of 194 patients with acute PQ poisoning, hospitalized between April 2012 and January 2014 at the First Affiliated Hospital of P.R. China Medical University (Shenyang, China), were selected and divided into survival and mortality groups. Logistic regression analysis, receiver operator characteristic (ROC) curve analysis and Kaplan-Meier curve were applied to evaluate the values of urine paraquat (PQ) concentration, dose of poison, arterial blood lactate and (APACHE) II score for predicting the prognosis of patients with acute PQ poisoning. Initial urine PQ concentration (C0), dose of poison, arterial blood lactate and APACHE II score of patients in the mortality group were significantly higher compared with the survival group (all P<0.05). Logistic regression analysis revealed that C0, dose of poison and arterial blood lactate correlated with mortality risk of acute PQ poisoning (all P<0.05). ROC curve analysis suggested that the areas under the curve (AUC) values of C0, dose of poison, arterial blood lactate and APACHE II score in predicting the mortality of patients within 28 days were 0.921, 0.887, 0.808 and 0.648, respectively. The AUC of C0 for predicting early and delayed mortality were 0.890 and 0.764, respectively. The AUC values of urine paraquat concentration the day after poisoning (Csec) and the rebound rate of urine paraquat concentration in predicting the mortality of patients within 28 days were 0.919 and 0.805, respectively. The 28-day survival rate of patients with C0 ≤32.2 µg/ml (42/71; 59.2%) was significantly higher when compared with patients with C0 >32.2 µg/ml (38/123; 30.9%). These results suggest that the initial urine PQ concentration may be the optimal index for predicting the prognosis of patients with acute PQ poisoning. Additionally, dose of poison, arterial blood lactate, Csec and rebound rate also have referential significance.
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