Evidence map›Paper›PMID 28672886›Full record

ArticleExperimental and therapeutic medicine2017

Resveratrol (3,5,4'-trihydroxystilbene) and its properties in oral diseases.

Donatella Perrone, Maria Pia Fuggetta, Fatima Ardito, Andrea Cottarelli, Anna De Filippis, Giampietro Ravagnan, Salvatore De Maria, Lorenzo Lo Muzio

Open access · diamondAbstract read
In one paragraph

Article in Experimental and therapeutic medicine, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
1.9field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 80 citations in OpenAlex.

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  19. Polyphenols andJournal of preventive medicine and hygiene · 2022
    Review
  20. Natural Compounds as Promising Adjuvant Agents in The Treatment of Gliomas.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Donatella PerroneDepartment of Clinical and Experimental Medicine, University of Foggia, I-71122 Foggia, Italy.
Maria Pia FuggettaInstitute of Translational Pharmacology, CNR-Area Torvergata, I-00133 Rome, Italy.
Fatima ArditoDepartment of Clinical and Experimental Medicine, University of Foggia, I-71122 Foggia, Italy.
Andrea CottarelliInstitute of Translational Pharmacology, CNR-Area Torvergata, I-00133 Rome, Italy.
Anna De FilippisDepartment of Experimental Medicine, Second University of Napoli, Napoli, I-80131 Naples, Italy.
Giampietro RavagnanGlures srl. Operative Unit-Biochemical and Biophysical Department, I-80138 Naples, Italy.
Salvatore De MariaGlures srl. Operative Unit-Biochemical and Biophysical Department, I-80138 Naples, Italy.
Lorenzo Lo MuzioDepartment of Clinical and Experimental Medicine, University of Foggia, I-71122 Foggia, Italy.
University of Foggia · ITGeophysical Laboratory · USIstituto di Farmacologia Traslazionale · ITUniversity of Naples Federico II · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Health promotion strategies and lifestyle changes are important in disease prevention. Oral health has received a large amount of attention previously as it is a fundamental component of general health and it contributes to the quality of life. Therefore, the study of associations between diet, health and the presence of bioactive compounds in food is receiving a substantial amount of attention. In the present review the effects and targets of a natural polyohenolic stilbenoid compound; resveratrol (3,5,4'-trihydroxystilbene; RSV) is assessed, and the future prospects for RSV in promoting oral health are considered. RSV is a phytoalexin, synthesized by a wide range of plants and abundantly extracted in grape skin, it has been purported to exert a multiplicity of anti-inflammatory, anti-viral, anti-microbial, estrogenic, anticancer, cardioprotective, neuroprotective and immunomodulatory functions. In this review, following an introduction documenting the biochemistry of RSV and RSV glucosides, the bioavailability and pharmacokinetics of RSV are described. Considering its multiple properties, the present review has focused on the potential benefits of RSV as an antioxidant and chemopreventive agent.

Indexed as

chemopreventionoral diseaseoral squamous cell carcinomaoxidative stressresveratrol

Identifiers

PMID28672886
PMCPMC5488484
OpenAlexW2616238336

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.