Evidence map›Paper›PMID 28672849›Full record

ArticleJournal of functional biomaterials2017

Synergy of Iron Chelators and Therapeutic Peptide Sequences Delivered via a Magnetic Nanocarrier.

Gayani S Abayaweera, Hongwang Wang, Tej B Shrestha, Jing Yu, Kyle Angle, Prem Thapa, Aruni P Malalasekera, Leila Maurmann, Deryl L Troyer, Stefan H Bossmann

Abstract read
In one paragraph

Article in Journal of functional biomaterials, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gayani S AbayaweeraDepartment of Chemistry, Kansas State University, Manhattan, KS 66041, USA. gsa2014a@gmail.com.
Hongwang WangDepartment of Chemistry, Kansas State University, Manhattan, KS 66041, USA. hongwang@ksu.edu.
Tej B Shresthatbs3@ksu.edu (T.B.S.). yujing0415@ksu.edu.
Jing YuDepartment of Chemistry, Kansas State University, Manhattan, KS 66041, USA. kja2665@truman.edu.
Kyle AngleDepartment of Chemistry, Kansas State University, Manhattan, KS 66041, USA. aruni@ksu.edu.
Prem ThapaMicroscopy and Analytical Imaging Laboratory, University of Kansas, Lawrence, KS 66045, USA. leila76@ksu.edu.
Aruni P MalalasekeraDepartment of Chemistry, Kansas State University, Manhattan, KS 66041, USA. troyer@vet.k-state.edu.
Leila MaurmannDepartment of Chemistry, Kansas State University, Manhattan, KS 66041, USA. psthapa@ku.edu.
Deryl L Troyertbs3@ksu.edu (T.B.S.). troyer@vet.k-state.edu.
Stefan H BossmannDepartment of Chemistry, Kansas State University, Manhattan, KS 66041, USA. sbossman@ksu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Here, we report the synthesis, characterization, and efficacy study of Fe/Fe₃O₄-nanoparticles that were co-labeled with a tumor-homing and membrane-disrupting oligopeptide and the iron-chelator Dp44mT, which belongs to the group of the thiosemicarbazones. Dp44mT and the peptide sequence PLFAERL(

Indexed as

breast cancercell viability studyiron chelatoriron/iron oxide core/shell nanoparticletherapeutic peptide sequence

Identifiers

PMID28672849
PMCPMC5618274

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.