Evidence map›Paper›PMID 28672848›Full record

ArticleMolecules (Basel, Switzerland)2017

Mechanism Exploration of Arylpiperazine Derivatives Targeting the 5-HT

Feng Lin, Feng Li, Chao Wang, Jinghui Wang, Yinfeng Yang, Ling Yang, Yan Li

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Molecular Docking Assessment of Cathinones as 5-HTMolecules (Basel, Switzerland) · 2023
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Feng LinKey Laboratory of Xinjiang Endemic Phytomedicine Resources, Pharmacy School, Shihezi University, Shihezi 832002, Xinjiang, China. fenglin_dut@yeah.net.
Feng LiDepartment of Civil Engineering, Henan Institute of Engineering, Zhengzhou 451191, Henan, China. fengli@haue.edu.cn.
Chao WangKey Laboratory of Industrial Ecology and Environmental Engineering (MOE), Faculty of Chemical, Environmental and Biological Science and Technology, Dalian University of Technology, Dalian 116024, Liaoning, China. chaowang_dlou@163.com.
Jinghui WangKey Laboratory of Industrial Ecology and Environmental Engineering (MOE), Faculty of Chemical, Environmental and Biological Science and Technology, Dalian University of Technology, Dalian 116024, Liaoning, China. jhwang_dlut@163.com.
Yinfeng YangKey Laboratory of Industrial Ecology and Environmental Engineering (MOE), Faculty of Chemical, Environmental and Biological Science and Technology, Dalian University of Technology, Dalian 116024, Liaoning, China. yinfengyang@yeah.net.
Ling YangInstitute of Interdisciplinary Integrative Medicine Research, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. yling@dicp.ac.cn.
Yan LiKey Laboratory of Xinjiang Endemic Phytomedicine Resources, Pharmacy School, Shihezi University, Shihezi 832002, Xinjiang, China. yanli@dlut.edu.cn.
Dalian University of Technology · CNHenan University of Engineering · CNShanghai University of Traditional Chinese Medicine · CNShihezi University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As a G-protein coupled receptor, the 5-hydroxytryptamine 2A (5-HT

Indexed as

Binding SitesCatalytic DomainComputational BiologyComputer SimulationDrug DesignHumansModels, MolecularMolecular ConformationMolecular Docking SimulationMolecular Dynamics SimulationPiperazinesQuantitative Structure-Activity RelationshipReceptor, Serotonin, 5-HT2BSerotonin 5-HT2 Receptor AntagonistsPiperazinesReceptor, Serotonin, 5-HT2BSerotonin 5-HT2 Receptor Antagonists3D-QSAR5-HT2A receptorarylpiperazine derivativedepressionmolecular dockingmolecular dynamics

Identifiers

PMID28672848
PMCPMC6152085
OpenAlexW2690930232

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.