ArticleMolecules (Basel, Switzerland)2017
Novel Sulfamide-Containing Compounds as Selective Carbonic Anhydrase I Inhibitors.
Article in Molecules (Basel, Switzerland), 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Novel 2,4-Dichloro-5-sulfamoylbenzoic Acid Oxime Esters: First Studies as Potential Human Carbonic Anhydrase Inhibitors.ACS medicinal chemistry letters · 2024Article
- Cloning, characterization, and inhibition of the novel β-carbonic anhydrase from parasitic blood fluke,Journal of enzyme inhibition and medicinal chemistry · 2023Article
- Repurposing of World-Approved Drugs for Potential Inhibition against Human Carbonic Anhydrase I: A Computational Study.International journal of molecular sciences · 2023Article
- Biochemical and Biophysical Characterization of Carbonic Anhydrase VI from Human Milk and Saliva.The protein journal · 2022Article
- Novel Insights on Human Carbonic Anhydrase Inhibitors Based on Coumalic Acid: Design, Synthesis, Molecular Modeling Investigation, and Biological Studies.International journal of molecular sciences · 2022Article
- Synthesis,Journal of molecular structure · 2022Article
- Synthesis and Biological Evaluation of Novel Benzhydrylpiperazine-Coupled Nitrobenzenesulfonamide Hybrids.ACS omega · 2021Article
- Toxicity evaluation of sulfamides and coumarins that efficiently inhibit human carbonic anhydrases.Journal of enzyme inhibition and medicinal chemistry · 2020Article
- Sulfonamide Inhibition Studies of a New β-Carbonic Anhydrase from the Pathogenic ProtozoanInternational journal of molecular sciences · 2018Article
- Synthesis of novel benzenesulfamide derivatives with inhibitory activity against human cytosolic carbonic anhydrase I and II and Vibrio cholerae α- and β-class enzymes.Journal of enzyme inhibition and medicinal chemistry · 2018Article
- Cloning, Characterization and Anion Inhibition Studies of a β-Carbonic Anhydrase from the Pathogenic ProtozoanMolecules (Basel, Switzerland) · 2018Article
- Synthesis, Spectroscopic Characterization, andMolecules (Basel, Switzerland) · 2018Article
- Novel 6- and 7-Substituted Coumarins with Inhibitory Action against Lipoxygenase and Tumor-Associated Carbonic Anhydrase IX.Molecules (Basel, Switzerland) · 2018Article
- Potent and Selective Carboxylic Acid Inhibitors of Tumor-Associated Carbonic Anhydrases IX and XII.Molecules (Basel, Switzerland) · 2017Article
- Special Issue: Sulfonamides.Molecules (Basel, Switzerland) · 2017Article
- Article
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12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The development of isoform selective inhibitors of the carbonic anhydrase (CA; EC 4.2.1.1) enzymes represents the key approach for the successful development of druggable small molecules. Herein we report a series of new benzenesulfamide derivatives (-NH-SO₂NH₂) bearing the 1-benzhydrylpiperazine tail and connected by means of a β-alanyl or nipecotyl spacer. All compounds
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