Evidence map›Paper›PMID 28672216›Full record

ArticleDrug and alcohol dependence2017

Cumulative contextual risk at birth and adolescent substance initiation: Peer mediation tests.

W Alex Mason, Irina Patwardhan, Gail L Smith, Mary B Chmelka, Jukka Savolainen, Stacy-Ann A January, Jouko Miettunen, Marjo-Riitta Järvelin

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. School Climate as a Universal Intervention to Prevent Substance Use Initiation in Early Adolescence: A Longitudinal Study.Health education & behavior : the official publication of the Society for Public Health Education · 2020
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

W Alex MasonBoys Town, National Research Institute for Child and Family Studies, Boys Town, NE 68010, USA. Electronic address: walter.mason@boystown.org.
Irina PatwardhanBoys Town, National Research Institute for Child and Family Studies, Boys Town, NE 68010, USA. Electronic address: irina.patwardhan@boystown.org.
Gail L SmithBoys Town, National Research Institute for Child and Family Studies, Boys Town, NE 68010, USA. Electronic address: gail.smith@boystown.org.
Mary B ChmelkaBoys Town, National Research Institute for Child and Family Studies, Boys Town, NE 68010, USA. Electronic address: mary.chmelka@boystown.org.
Jukka SavolainenInter-University Consortium for Political and Social Research (ICPSR), Institute for Social Research, University of Michigan, Ann Arbor, MI 48106, USA. Electronic address: jsavolai@umich.edu.
Stacy-Ann A JanuaryDepartment of Psychology, University of South Carolina, Columbia, SC 29208, USA. Electronic address: sajanuary@sc.edu.
Jouko MiettunenCenter for Life Course Health Research, University of Oulu, Oulu, Finland and Medical Research Center Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland. Electronic address: jouko.miettunen@oulu.fi.
Marjo-Riitta JärvelinDepartment of Epidemiology and Biostatistics, MRC PHE Centre for Environment and Health, School of Public Health, Imperial College London, UK; Center for Life Course Epidemiology, Faculty of Medicine, P.O. Box 5000, FI-90014 University of Oulu, Finland; Biocenter Oulu, University of Oulu, Finland; Unit of Primary Care, Oulu University Hospital, Oulu, Finland. Electronic address: m.jarvelin@imperial.ac.uk.

Funding

Role of Childhood Cumulative Risk in Substance Misuse and Co-occurring ProblemsR01DA038450 · NIDA · FATHER FLANAGAN'S BOYS' HOME · PI MASON, W ALEX, SAVOLAINEN, JUKKA K · 2014 to 2016
$738k
NIDA NIH HHS R01 DA038450
6 · The paper itself

Abstract

backgroundChildren who experience multiple adversities, such as prenatal exposure to drugs and poverty, early in development are at increased risk for the early initiation of alcohol and cigarette use. However, studies that examine potentially malleable processes associated with substance use initiation in the context of exposure to cumulative stressors are scant. This study examined associations between cumulative contextual risk at birth and initiation of alcohol and cigarette use in adolescence, testing childhood peer marginalization and peer aggression and behavior problems as mediating mechanisms. Analyses further adjusted for fearfulness/inhibition and hyperactivity/distractibility to determine if the hypothesized mediating mechanisms were significant after accounting for temperamental characteristics associated with substance initiation.

methodsParticipants were 6190 adolescents from the Northern Finland Birth Cohort 1986 Study. Data were collected on cumulative contextual risk (parent reports), substance initiation (adolescent reports), childhood peer processes and behavior problems (teacher reports), and temperamental characteristics (teacher reports). Novel discrete-time survival mediation analysis was conducted to test the hypothesized mediating mechanisms.

resultsInitial analyses showed that the associations between cumulative contextual risk and both alcohol and cigarette initiation were mediated by childhood peer processes and behavior problems; however, the indirect effects became statistically non-significant after adding the temperament variables, which themselves predicted substance initiation.

conclusionsTargeting peer processes may not be an effective way to interrupt pathways leading from early contextual risk to substance initiation. Instead, early screening and intervention efforts to delay substance initiation may need to be tailored to the individual temperamental characteristics of targeted participants.

Indexed as

Peer GroupRisk-TakingAdolescentAdolescent BehaviorChildCohort StudiesFemaleFinlandHumansMaleProblem BehaviorSubstance-Related DisordersCumulative riskPeerSubstance initiationTemperament

Identifiers

PMID28672216
PMCPMC5538186

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.