ArticlePloS one2017
An adjustable predictive score of graft survival in kidney transplant patients and the levels of risk linked to de novo donor-specific anti-HLA antibodies.
Article in PloS one, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed.
- Trial
- Prediction system for risk of allograft loss in patients receiving kidney transplants: international derivation and validation study.BMJ (Clinical research ed.) · 2019Trial
- Unboxing iBox: A Critical Appraisal of Its Measurement Properties for Predicting Kidney Allograft Failure.Kidney medicine · 2026Review
- External Validation of an Easy-to-Use, Adjustable Score for Short- to Long-term Prediction of Kidney Graft Failure.Transplantation direct · 2025Article
- Outcomes After Kidney Transplantation in Antineutrophil Cytoplasmic Autoantibody-Associated Renal Vasculitis.Kidney international reports · 2025Article
- Outcomes After Kidney Transplantation in Antiglomerular Basement Membrane Disease.Kidney international reports · 2025Article
- Predicting Kidney Transplantation Outcomes from Donor and Recipient Characteristics at Time Zero: Development of a Mobile Application for Nephrologists.Journal of clinical medicine · 2024Article
- Comparison of artificial intelligence and human-based prediction and stratification of the risk of long-term kidney allograft failure.Communications medicine · 2022Article
- Surrogate Endpoints for Late Kidney Transplantation Failure.Transplant international : official journal of the European Society for Organ Transplantation · 2022Article
- Prognostic value for long-term graft survival of estimated glomerular filtration rate and proteinuria quantified at 3 months after kidney transplantation.Clinical kidney journal · 2020Article
- Identification and weighting of kidney allocation criteria: a novel multi-expert fuzzy method.BMC medical informatics and decision making · 2019Article
- Alloimmunogenicity of an isolated MHC allele is affected by the context of MHC mismatch in a murine model.Transfusion · 2019Article
- A Prognostic Tool for Individualized Prediction of Graft Failure Risk within Ten Years after Kidney Transplantation.Journal of transplantation · 2019Article
- Qualified prediction system for allograft failure in real world settings: extended validation study.BMJ medicineArticle
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Most predictive models and scores of graft survival in renal transplantation include factors known before transplant or at the end of the first year. They cannot be updated thereafter, even in patients developing donor-specific anti-HLA antibodies and acute rejection.We developed a conditional and adjustable score for prediction of graft failure (AdGFS) up to 10 years post-transplantation in 664 kidney transplant patients. AdGFS was externally validated and calibrated in 896 kidney transplant patients.The final model included five baseline factors (pretransplant non donor-specific anti-HLA antibodies, donor age, serum creatinine measured at 1 year, longitudinal serum creatinine clusters during the first year, proteinuria measured at 1 year), and two predictors updated over time (de novo donor-specific anti-HLA antibodies and first acute rejection). AdGFS was able to stratify patients into four risk-groups, at different post-transplantation times. It showed good discrimination (time-dependent ROC curve at ten years: 0.83 (CI95% 0.76-0.89).
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