Evidence map›Paper›PMID 28671678›Full record

ArticleNature chemical biology2017

Molecular basis of the evolution of alternative tyrosine biosynthetic routes in plants.

Craig A Schenck, Cynthia K Holland, Matthew R Schneider, Yusen Men, Soon Goo Lee, Joseph M Jez, Hiroshi A Maeda

Abstract read
PubMed Publisher
In one paragraph

Article in Nature chemical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.2field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 57 citations in OpenAlex.

  1. Article
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  6. Evolution of aromatic amino acid metabolism in plants: a key driving force behind plant chemical diversity in aromatic natural products.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
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  20. Robust predictions of specialized metabolism genes through machine learning.Proceedings of the National Academy of Sciences of the United States of America · 2019
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Craig A SchenckDepartment of Botany, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Cynthia K HollandDepartment of Biology, Washington University in St. Louis, St. Louis, Missouri, USA.
Matthew R SchneiderDepartment of Botany, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Yusen MenDepartment of Botany, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Soon Goo LeeDepartment of Biology, Washington University in St. Louis, St. Louis, Missouri, USA.
Joseph M JezDepartment of Biology, Washington University in St. Louis, St. Louis, Missouri, USA.
Hiroshi A MaedaDepartment of Botany, University of Wisconsin-Madison, Madison, Wisconsin, USA.
University of Wisconsin–Madison · USWashington University in St. Louis · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

L-Tyrosine (Tyr) is essential for protein synthesis and is a precursor of numerous specialized metabolites crucial for plant and human health. Tyr can be synthesized via two alternative routes by different key regulatory TyrA family enzymes, prephenate dehydrogenase (PDH, also known as TyrA

Indexed as

Evolution, MolecularSignal TransductionAmino Acid SequenceCrystallography, X-RayPhylogenyPlantsPrephenate DehydrogenaseSequence AlignmentSubstrate SpecificityTyrosinecyclohexadienyl dehydrogenasePrephenate DehydrogenaseTyrosine

Identifiers

PMID28671678
OpenAlexW2650743363

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.