Evidence map›Paper›PMID 28671636›Full record

ArticleInternational journal of molecular sciences2017

Neuroprotective and Anti-Inflammatory Activities of Allyl Isothiocyanate through Attenuation of JNK/NF-κB/TNF-α Signaling.

Lalita Subedi, Ramu Venkatesan, Sun Yeou Kim

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 1 synthesis or guideline pooled it, 103 citations in OpenAlex.

  1. Pooled it
  2. Glucosinolate Derivatives: Emerging Anti-Inflammatory Agents.Pharmaceuticals (Basel, Switzerland) · 2026
    Review
  3. Organosulfur Compounds: Potential Therapeutics for Parkinson's Disease.CNS & neurological disorders drug targets · 2026
    Review
  4. Mitigation ofJournal of microbiology and biotechnology · 2025
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Review
  10. Immunomodulatory Effects and Regulatory Mechanisms of (Journal of agricultural and food chemistry · 2024
    Article
  11. Article
  12. Article
  13. Therapeutic Candidates for Alzheimer's Disease: Saponins.International journal of molecular sciences · 2023
    Review
  14. Article
  15. Article
  16. Article
  17. Frontiers in microbiology · 2023
    Article
  18. Review
  19. Wasabi (Foods (Basel, Switzerland) · 2022
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Lalita SubediLaboratory of Pharmacognosy, College of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, #191, Hambakmoero, Yeonsu-gu, Incheon 21936, Korea. subedilali@gmail.com.
Ramu VenkatesanLaboratory of Pharmacognosy, College of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, #191, Hambakmoero, Yeonsu-gu, Incheon 21936, Korea. vramamoorthysree@gmail.com.
Sun Yeou KimLaboratory of Pharmacognosy, College of Pharmacy and Gachon Institute of Pharmaceutical Sciences, Gachon University, #191, Hambakmoero, Yeonsu-gu, Incheon 21936, Korea. sunnykim@gachon.ac.kr.
Gachon University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allyl isothiocyanate (AITC), present in

Indexed as

AnimalsAnti-Inflammatory AgentsCell LineCell SurvivalCoumaric AcidsCyclooxygenase 2DinoprostoneInflammation MediatorsIsothiocyanatesJNK Mitogen-Activated Protein KinasesLipopolysaccharidesMAP Kinase Signaling SystemMiceMicrogliaNerve Growth FactorNeuritesallyl isothiocyanateAnti-Inflammatory AgentsCoumaric AcidsCyclooxygenase 2DinoprostoneInflammation MediatorsIsothiocyanatesJNK Mitogen-Activated Protein KinasesLipopolysaccharidesNerve Growth FactorNeuroprotective AgentsNeurotoxinsNF-kappa BNitric OxideNitric Oxide Synthase Type IIPlant Extractssinapinic acidToll-Like Receptor 4Tumor Necrosis Factor-alphaallyl isothiocyanateastrocytemicroglianeuroinflammationneuronneuroprotection

Identifiers

PMID28671636
PMCPMC5535914
OpenAlexW2732175055

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.