Evidence map›Paper›PMID 28671607›Full record

ReviewInternational journal of molecular sciences2017

Diabetes and Wound Angiogenesis.

Uzoagu A Okonkwo, Luisa A DiPietro

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of molecular sciences, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 448 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
448citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

448 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Pooled it
  5. Review
  6. Article
  7. A CD14-Targeting In Situ Hydrogel Directs Macrophage Reprogramming to Minimize Scar Formation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
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388 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Uzoagu A OkonkwoDepartment of Microbiology and Immunology, University of Illinois at Chicago College of Medicine, Chicago, IL 60612, USA. uokonk2@uic.edu.
Luisa A DiPietroCenter for Wound Healing and Tissue Regeneration, University of Illinois at Chicago College of Dentistry, Chicago, IL 60612, USA. Ldipiet@uic.edu.

Funding

ANGIOGENESIS IN WOUND REPAIRR01GM050875 · NIGMS · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DIPIETRO, LUISA A · 1999 to 2020
$6.6M
MicroRNA regulation of the injury response in oral mucosaR21DE025926 · NIDCR · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DIPIETRO, LUISA A, ZHOU, XIAOFENG · 2016 to 2017
$440k
NIDCR NIH HHS R21 DE025926NIGMS NIH HHS R01 GM050875
6 · The paper itself

Abstract

Diabetes Mellitus Type II (DM2) is a growing international health concern with no end in sight. Complications of DM2 involve a myriad of comorbidities including the serious complications of poor wound healing, chronic ulceration, and resultant limb amputation. In skin wound healing, which has definite, orderly phases, diabetes leads to improper function at all stages. While the etiology of chronic, non-healing diabetic wounds is multi-faceted, the progression to a non-healing phenotype is closely linked to poor vascular networks. This review focuses on diabetic wound healing, paying special attention to the aberrations that have been described in the proliferative, remodeling, and maturation phases of wound angiogenesis. Additionally, this review considers therapeutics that may offer promise to better wound healing outcomes.

Indexed as

Neovascularization, PhysiologicWound HealingAnimalsBlood VesselsDiabetes MellitusHumansangiogenesisdiabeteswound healing

Identifiers

PMID28671607
PMCPMC5535911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.