Evidence map›Paper›PMID 28671330›Full record

ArticleJournal of medical primatology2017

Cytomegaloviral hypophysitis in a simian immunodeficiency virus-infected rhesus macaque (Macacca mulatta).

Melissa R Berg, Michael A Owston, Marie-Claire Gauduin, Basel T Assaf, Anne D Lewis, Edward J Dick

Open access · greenAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical primatology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Melissa R BergSouthwest National Primate Research Center at the Texas Biomedical Research Institute, San Antonio, TX, USA.ORCID 0000-0002-0053-9503
Michael A OwstonSouthwest National Primate Research Center at the Texas Biomedical Research Institute, San Antonio, TX, USA.
Marie-Claire GauduinSouthwest National Primate Research Center at the Texas Biomedical Research Institute, San Antonio, TX, USA.
Basel T AssafOregon National Primate Research Center, Beaverton, OR, USA.
Anne D LewisOregon National Primate Research Center, Beaverton, OR, USA.
Edward J DickSouthwest National Primate Research Center at the Texas Biomedical Research Institute, San Antonio, TX, USA.
Oregon National Primate Research Center · USTexas Biomedical Research Institute · US

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
Trans-complementing papillioma virus for AIDS vaccineR01AI117862 · NIAID · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI GAUDUIN, MARIE-CLAIRE ELISABETH · 2015 to 2018
$3.4M
NIAID NIH HHS R01 AI117862NIH HHS P51 OD011092NIH HHS P51 OD011133
6 · The paper itself

Abstract

Rhesus macaques experimentally infected with Simian Immunodeficiency Virus (SIV) experience immunosuppression and often opportunistic infection. Among the most common opportunistic infections are rhesus cytomegalovirus (RhCMV), a ubiquitous betaherpesvirus that undergoes continuous low-level replication in immunocompetent monkeys. Upon SIV-mediated immunodeficiency, RhCMV reactivates and results in lesions in numerous organ systems including the nervous and reproductive systems. We report the first case of cytomegaloviral hypophysitis in a SIV-immunocompromised rhesus macaque.

Indexed as

Immunocompromised HostMacaca mulattaAnimalsCytomegalovirusFemaleHypophysitisOpportunistic InfectionsSimian Acquired Immunodeficiency SyndromeSimian Immunodeficiency Viruscytomegalovirusinclusionsintra-cytoplasmicintranuclearmodelnon-human primatepituitaryviral

Identifiers

PMID28671330
PMCPMC5673561
OpenAlexW2727692864

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.