ArticleNature communications2017
Transplantation of enteric nervous system stem cells rescues nitric oxide synthase deficient mouse colon.
Article in Nature communications, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
38 citing papers in PubMed, 82 citations in OpenAlex.
- Enteric nervous system and inflammatory bowel disease.Gastroenterology report · 2026Review
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- Effects of aged garlic extract on aging?related changes in gastrointestinal function and enteric nervous system cells.Experimental and therapeutic medicine · 2025Article
- Article
- Tissue engineering and regenerative medicine approaches in colorectal surgery.Annals of coloproctology · 2024Review
- Enteric neural stem cell transplant restores gut motility in mice with Hirschsprung disease.JCI insight · 2024Article
- Role ofHeliyon · 2024Article
- Autologous cell transplantation for treatment of colorectal aganglionosis in mice.Nature communications · 2024Article
- Updates and Challenges in ENS Cell Therapy for the Treatment of Neurointestinal Diseases.Biomolecules · 2024Review
- Analysis of Gut Characteristics and Microbiota Changes with Maternal Supplementation in a Neural Tube Defect Mouse Model.Nutrients · 2023Article
- Enteric neurospheres retain the capacity to assemble neural networks with motile and metamorphic gliocytes and ganglia.Stem cell research & therapy · 2023Article
- Review
- Transplanted ENSCs form functional connections with intestinal smooth muscle and restore colonic motility in nNOS-deficient mice.Stem cell research & therapy · 2023Article
- Regenerative medicine: current research and perspective in pediatric surgery.Pediatric surgery international · 2023Review
- Macrophage regulation of the "second brain": CD163 intestinal macrophages interact with inhibitory interneurons to regulate colonic motility - evidence from theFrontiers in immunology · 2023Article
- Schwann Cells in the Aganglionic Colon of Hirschsprung Disease Can Generate Neurons for Regenerative Therapy.Stem cells translational medicine · 2022Article
- Cardiac Neural Crest and Cardiac Regeneration.Cells · 2022Review
- Review
- Human Pluripotent Stem Cell-Based Models for Hirschsprung Disease: From 2-D Cell to 3-D Organoid Model.Cells · 2022Review
- Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
Abstract
Enteric nervous system neuropathy causes a wide range of severe gut motility disorders. Cell replacement of lost neurons using enteric neural stem cells (ENSC) is a possible therapy for these life-limiting disorders. Here we show rescue of gut motility after ENSC transplantation in a mouse model of human enteric neuropathy, the neuronal nitric oxide synthase (nNOS
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.