Evidence map›Paper›PMID 28670540›Full record

ArticleIndian journal of endocrinology and metabolism

Effect of Vitamin D Supplementation on Vascular Functions and Oxidative Stress in Type 2 Diabetic Patients with Vitamin D Deficiency.

Nishanthi Anandabaskar, Sandhiya Selvarajan, Steven Aibor Dkhar, Sadish Kumar Kamalanathan, Kadhiravan Tamilarasu, Zachariah Bobby

Abstract read
In one paragraph

Article in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Dietary Supplementation with 25-Hydroxyvitamin DAntioxidants (Basel, Switzerland) · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Observational
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Nishanthi AnandabaskarDepartment of Pharmacology, JIPMER, Puducherry, India.
Sandhiya SelvarajanDepartment of Clinical Pharmacology, JIPMER, Puducherry, India.
Steven Aibor DkharDepartment of Clinical Pharmacology, JIPMER, Puducherry, India.
Sadish Kumar KamalanathanDepartment of Endocrinology, JIPMER, Puducherry, India.
Kadhiravan TamilarasuDepartment of Medicine, JIPMER, Puducherry, India.
Zachariah BobbyDepartment of Biochemistry, JIPMER, Puducherry, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVitamin D levels are reported to have an inverse liaison with the risk of cardiovascular diseases. Hence, we aimed to evaluate the effect of Vitamin D supplementation on changes in vascular functions and oxidative stress in type 2 diabetic patients with Vitamin D deficiency. SUBJECTS AND

methodsOne hundred and three patients with type 2 diabetes attending endocrinology outpatients department in a tertiary care hospital were screened for Vitamin D deficiency. Patients with serum 25-hydroxy Vitamin D levels <20 ng/ml were considered as deficient and were administered 60,000 IU of oral Vitamin D

resultsAmong 103 patients with type 2 diabetes, 75 (72.82%) were found to have Vitamin D deficiency. Amidst these patients, carotid-femoral pulse wave velocity (991.6 ± 161.82 vs. 899.29 ± 151.86,

conclusionThe present study shows that oral Vitamin D supplementation of 60,000 IU/week for 8 weeks significantly improves vascular functions and reduces oxidative stress in type 2 diabetic patients with Vitamin D deficiency.

Indexed as

Arterial stiffnessoxidative stresstype 2 diabetes mellitusVitamin D deficiency

Identifiers

PMID28670540
PMCPMC5477444

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.