Evidence map›Paper›PMID 28670539›Full record

ArticleIndian journal of endocrinology and metabolism

Increased Levels of Serum Interleukin-17 in Patients with Hashimoto's Thyroiditis.

Fatemeh Esfahanian, Roghayeh Ghelich, Hoda Rashidian, Zohreh Jadali

Abstract read
In one paragraph

Article in Indian journal of endocrinology and metabolism. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. The Role ofPathogens (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Improving Hashimoto's thyroiditis by eradicatingTherapeutic advances in endocrinology and metabolism · 2020
    Article
  16. IL-17 and limits of success.Cellular immunology · 2019
    Review
  17. Observational
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Fatemeh EsfahanianEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Roghayeh GhelichDepartment of Endocrinology, Imam Khomeini General Hospital, Tehran, Iran.
Hoda RashidianEndocrinology and Metabolism Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.
Zohreh JadaliDepartment of Immunology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCD4+ T-cells play important roles in the pathogenesis of Hashimoto's thyroiditis (HT). However, there is limited data about characteristics and function of the newly interleukin (IL)-17-producing T-helper cells in this common autoimmune thyroid disorder.

aimThe purpose of this study was to assess the levels of T-helper 17-related cytokines in sera of patients with HT. MATERIALS AND

methodsCytokine concentrations were measured in 48 patients with overt (

resultsThe serum levels of IL-17 were significantly higher in patients than controls (

conclusionThese results suggest that IL-17 could play some role in the pathogenesis of HT.

Indexed as

AutoimmunitycytokineHashimoto's thyroiditisT-lymphocyte

Identifiers

PMID28670539
PMCPMC5477443

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.