Evidence map›Paper›PMID 28670397›Full record

ArticleAmerican journal of translational research2017

Combined administration of a sedative dose sevoflurane and 60% oxygen reduces inflammatory responses to sepsis in animals and in human PMBCs.

Er-Fei Zhang, Zuo-Xu Hou, Tian Shao, Wan-Wan Yang, Bin Hu, Xiao-Xia Wang, Ze-Xin Zhang, Yi Huang, Li-Ze Xiong, Li-Chao Hou

Open access · greenAbstract read
PubMed Full text at PMC
In one paragraph

Article in American journal of translational research, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Er-Fei ZhangDepartment of Anesthesiology and Critical Care Medicine, Xijing Hospital, The Fourth Military Medical UniversityXi'an 710032, Shaanxi Province, P. R. China.
Zuo-Xu HouDepartment of Aerospace Medicine, The Fourth Military Medical UniversityXi'an 710032, Shaanxi, P. R. China.
Tian ShaoDepartment of Anesthesiology and Critical Care Medicine, Xijing Hospital, The Fourth Military Medical UniversityXi'an 710032, Shaanxi Province, P. R. China.
Wan-Wan YangDepartment of Anesthesiology and Critical Care Medicine, Xijing Hospital, The Fourth Military Medical UniversityXi'an 710032, Shaanxi Province, P. R. China.
Bin HuDepartment of Anesthesiology, The Affiliated Hospital of Yan'an UniversityYan'an 716000, Shaanxi Province, P. R. China.
Xiao-Xia WangDepartment of Anesthesiology and Critical Care Medicine, Xijing Hospital, The Fourth Military Medical UniversityXi'an 710032, Shaanxi Province, P. R. China.
Ze-Xin ZhangDepartment of Anesthesiology and Critical Care Medicine, Xijing Hospital, The Fourth Military Medical UniversityXi'an 710032, Shaanxi Province, P. R. China.
Yi HuangDepartment of Anesthesiology and Critical Care Medicine, Xijing Hospital, The Fourth Military Medical UniversityXi'an 710032, Shaanxi Province, P. R. China.
Li-Ze XiongDepartment of Anesthesiology and Critical Care Medicine, Xijing Hospital, The Fourth Military Medical UniversityXi'an 710032, Shaanxi Province, P. R. China.
Li-Chao HouDepartment of Anesthesiology and Critical Care Medicine, Xijing Hospital, The Fourth Military Medical UniversityXi'an 710032, Shaanxi Province, P. R. China.
Xijing Hospital · CNYan'an University · CNAir Force Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our study aims to investigate the effects of the inhalation of subanesthestic doses of sevoflurane combined with oxygen on sepsis. Male Sprague-Dawley rats or Male ICR/Km mice underwent caecal ligation and puncture (CLP) or intraperitoneal injection of lipopolysccharide (LPS) to induce sepsis, while sham rats were used as control. Then, rats were treated with the inhalation of sevoflurane in oxygen; and air or 100% oxygen was used as control. Seven-day survival, lung injury and inflammatory factors were assessed. In this

Indexed as

Acute lung injuryhuman peripheral blood mononuclear cellsNF-κBsepsissevoflurane

Identifiers

PMID28670397
PMCPMC5489909
OpenAlexW2983897296

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.